5(6)-TAMRA SE | CAS No. 246256-50-8

5(6)-TAMRA SE

Basic Information

CAS Number

246256-50-8

Molecular Formula

C58H50N6O14

Molecular Weight

1055.05 g/mol

AD

Basic Physical Properties

O=C1CCC(=O)N1OC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(cc2Oc2c1ccc(c2)N(C)C)N(C)C.O=C1CCC(=O)N1OC(=O)c1ccc2c(c1)C(=O)OC12c2ccc(cc2Oc2c1ccc(c2)N(C)C)N(C)C

InChI

InChI=1S/2C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34;1-30(2)17-6-9-20-23(14-17)37-24-15-18(31(3)4)7-10-21(24)29(20)22-13-16(5-8-19(22)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h2*5-10,13-15H,11-12H2,1-4H3

InChIKey

UWQYEQKHQZYMMZ-UHFFFAOYSA-N

LogP

7.214800000000009

Topological Polar Surface Area

211.37999999999997 Ų

Hydrogen Bond Donor/Acceptor

0 / 20

Synonyms & References

English

  • 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester] *CAS 246256-50-8*
  • 5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester, mixed isomers
  • 5(6)-Carboxytetramethylrhodamine succinimidyl ester
  • (5(6)-TAMRASE
  • 5(6)-CARBOXYTETRAMETHYLRHODAMINE N-SUCCINIMIDYL ESTER
  • 9-[2-Carboxy-4(or 5)-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-3,6-bis(dimethylamino)-xanthylium inner salt
  • 5(6)-TAMRA-SEor5(6)-TAMRA-NHS
  • 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester] *Mixed isomers*
  • 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
  • 5(6)-TAMRA, SE
  • C29H25N3O7
  • 5(6)-TAMRA SE

MDL Number

MFCD00077324

FAQ

What are the physical and chemical properties of 5(6)-TAMRA SE (CAS: 246256-50-8)?

5(6)-TAMRA SE is a fluorescent dye with a molecular weight of approximately 637.6 g/mol. It exhibits excellent solubility in organic solvents such as DMSO and ethanol. Chemically, it shows high stability under basic conditions but is less stable in acidic environments. It is widely used in fluorescence labeling due to its strong red fluorescence and good photostability.

How is 5(6)-TAMRA SE (CAS: 246256-50-8) typically synthesized?

5(6)-TAMRA SE is typically synthesized by coupling a 5-carboxytetramethylrhodamine (TAMRA) dye to a suitable linker or carrier molecule. This process often involves chemical coupling reactions, such as amidation or esterification, using appropriate reagents and catalysts. The yield and selectivity depend on the specific synthesis protocol and the choice of starting materials.

What industries use 5(6)-TAMRA SE (CAS: 246256-50-8)?

5(6)-TAMRA SE is extensively used in various industries, including pharmaceuticals for drug screening and diagnostic applications, polymer science for labeling and tracking, sensing technologies for detecting specific analytes, and semiconductor industries for quality control and process monitoring. Its fluorescence properties make it particularly valuable in these fields.

What precautions should be taken when handling 5(6)-TAMRA SE (CAS: 246256-50-8)?

When handling 5(6)-TAMRA SE, appropriate personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to airborne particles. Spills should be cleaned up using appropriate solvents, and proper waste disposal procedures should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and guidelines.

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