(R,R)-Et-Duphos-Rh

Basic Information

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CAS Number

228121-39-9

Molecular Formula

C30H48BF4P2Rh-

Molecular Weight

660.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Insecticides

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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[B-](F)(F)(F)F.CCC1CCC(P1C2=CC=CC=C2P3C(CCC3CC)CC)CC.C1CC=CCCC=C1.[Rh]

InChI

InChI=1S/C22H36P2.C8H12.BF4.Rh/c1-5-17-13-14-18(6-2)23(17)21-11-9-10-12-22(21)24-19(7-3)15-16-20(24)8-4;1-2-4-6-8-7-5-3-1;2-1(3,4)5;/h9-12,17-20H,5-8,13-16H2,1-4H3;1-2,7-8H,3-6H2;;/q;;-1;/b;2-1-,8-7-;;/t17-,18-,19-,20-;;;/m1.../s1

InChIKey

XIOPHSBHVOCZMM-KYOOHHHUSA-N

LogP

10.573299999999993

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

414

Safety Information

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Sensitiveness

air sensitive

Synonyms & References

English

(1Z, 5Z)-cycloocta-1, 5-diene;(2R, 5R)-1-[2-[(2R, 5R)-2, 5-diethylphospholan-1-yl]phenyl]-2, 5-diethylphospholane;rhodium;tetrafluoroborate
(-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(CYCLOOCTADIENE)RHODIUM(L)TETRAFLUOROBORATE
228121-39-9
J-014866
(1Z,5Z)-cycloocta-1,5-diene;(2R,5R)-1-[2-[(2R,5R)-2,5-diethylphospholan-1-yl]phenyl]-2,5-diethylphospholane;rhodium;tetrafluoroborate
MFCD01862464
(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene(cyclooctadiene)rhodium(l) tetrafluoroborate
228121-39-9 (name error)
DTXSID50459685
(1Z,5Z)-cycloocta-1,5-diene,(2R,5R)-1-[2-[(2R,5R)-2,5-diethylphospholan-1-yl]phenyl]-2,5-diethylphospholane,rhodium,tetrafluoroborate
1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene(cyclooctadiene)rhodium(I) tetrafluoroborate
[(R,R)Ethyl-DuPhosRh(COD)]BF4
1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate
(R,R)-Et-DUPHOS-Rh

MDL Number

MFCD01862464

Customs Code

29310099

FAQ

What are the physical and chemical properties of (R,R)-Et-Duphos-Rh (CAS: 228121-39-9)?

(R,R)-Et-Duphos-Rh is a chiral rhodium complex with a crystalline form and a molecular weight of approximately 500 g/mol. It has limited water solubility and exhibits high reactivity in catalytic processes, making it suitable for asymmetric synthesis. The complex is known for its stability in air and light, but should be handled under inert conditions to preserve its reactivity.

How is (R,R)-Et-Duphos-Rh (CAS: 228121-39-9) typically synthesized?

(R,R)-Et-Duphos-Rh is synthesized using rhodium acetate and a chiral ligand. The synthetic route involves the coordination of the ligand to the rhodium center, followed by the exchange of the acetate ligand with a more reactive one, such as a phosphine. The process typically yields a high enantiomeric excess (ee) and is performed under inert conditions to ensure reactivity and selectivity.

What industries use (R,R)-Et-Duphos-Rh (CAS: 228121-39-9)?

(R,R)-Et-Duphos-Rh is primarily used in the pharmaceutical industry for the synthesis of chiral compounds, which are essential for drug development. It is also applied in the production of chiral monomers for polymer synthesis and in the development of chiral sensors and semiconductors, where its catalytic and reactivity properties are highly valued.

What precautions should be taken when handling (R,R)-Et-Duphos-Rh (CAS: 228121-39-9)?

When handling (R,R)-Et-Duphos-Rh, it should be done under a fume hood to avoid inhalation and contact with skin and eyes. Personal protective equipment (PPE) including gloves, safety goggles, and a lab coat is required. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.