2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone | CAS No. 2274-66-0

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone

Basic Information

CAS Number

2274-66-0

Molecular Formula

C8H4Cl4O

Molecular Weight

257.93 g/mol

AD

Basic Physical Properties

Boiling Point

310 °C at 760 mmHg

Density

1.535

Flash Point

130.2 °C

Refractive Index

1.577

C1=CC(=C(C=C1Cl)Cl)C(=O)C(Cl)Cl

InChI

InChI=1S/C8H4Cl4O/c9-4-1-2-5(6(10)3-4)7(13)8(11)12/h1-3,8H

InChIKey

LRXWJPURTZCTEH-UHFFFAOYSA-N

LogP

3.9798

Topological Polar Surface Area

17.07 Ų

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

195

Synonyms & References

English

  • AKOS022939727
  • W-109766
  • 2,4-Dichlorophenacylidene dichloride
  • 2,2,2,4-TETRACHLOROACETOPHENONE
  • CHEMBL4283949
  • Acetophenone,2,2',4'-tetrachloro-
  • 2274-66-0
  • NSC81222
  • O43MMI49GE
  • MFCD00018859
  • .ALPHA.,.ALPHA.,2',4'-TETRACHLOROACETOPHENONE
  • CAA27466
  • DTXSID9062300
  • NSC 81222
  • Q27285304
  • 2,2-Dichloro-1-(2,4-dichlorophenyl)ethan-1-one
  • CS-0206599
  • NSC-81222
  • Ethanone,2-dichloro-1-(2,4-dichlorophenyl)-
  • 2, 2-dichloro-1-(2, 4-dichlorophenyl)ethanone
  • BS-25387
  • 2,2-dichloro-1-(2,4-dichlorophenyl)ethanone
  • 2,2,2',4'-Tetrachloroacetophenone
  • EINECS 218-890-6
  • Ethanone, 2,2-dichloro-1-(2,4-dichlorophenyl)-
  • 2,2',4'-Tetrachloroacetophenone
  • FT-0609021
  • 2,4-Dichlorophenacylidene chloride
  • Acetophenone, 2,2,2',4'-tetrachloro-
  • UNII-O43MMI49GE
  • NS00027254

MDL Number

MFCD00018859

Customs Code

2914700090

FAQ

What are the physical and chemical properties of 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0)?

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) is a white crystalline solid with a molecular weight of 288.05 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is chemically stable but may react with strong bases, leading to the formation of chlorinated byproducts. It is used as a precursor in various organic synthesis reactions.

How is 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) typically synthesized?

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) is typically synthesized via a condensation reaction between 2,4-dichlorophenyl isocyanate and acetyl chloride. This process involves the use of triethylamine as a base and occurs at room temperature, providing good yields and selectivity. The reaction is monitored using thin-layer chromatography.

What industries use 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0)?

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various pharmaceuticals and polymers with specific functional groups. Additionally, it can be used in the production of sensors and semiconductors due to its reactive functional groups.

What precautions should be taken when handling 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0)?

When handling 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0), it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be carefully cleaned up using appropriate absorbent materials, and the area should be decontaminated. For detailed safety information, refer to the safety data sheet (SDS).

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