Compound Q&A

How is 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) typically synthesized?

Answer

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone
2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS: 2274-66-0) is typically synthesized via a condensation reaction between 2,4-dichlorophenyl isocyanate and acetyl chloride. This process involves the use of triethylamine as a base and occurs at room temperature, providing good yields and selectivity. The reaction is monitored using thin-layer chromatography.

About

CAS No 2274-66-0
English Name 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone
Molecular Formula C8H4Cl4O
Molecular Weight 257.93 g/mol
SMILES C1=CC(=C(C=C1Cl)Cl)C(=O)C(Cl)Cl
InChIKey LRXWJPURTZCTEH-UHFFFAOYSA-N
Last Updated: 2026-03-08 09:14

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