1-Aminocyclobutanecarboxylic acid

Basic Information

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CAS Number

22264-50-2

Molecular Formula

C5H9NO2

Molecular Weight

115.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

261 °C (dec.)

Boiling Point

434.2ºC at 760 mmHg

Density

1.2900

Water Solubility

Soluble to 100 mM in water.

Flash Point

216.4ºC

Refractive Index

1.712

SMILES

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C1CC(C1)(C(=O)O)N

InChI

InChI=1S/C5H9NO2/c6-5(4(7)8)2-1-3-5/h1-3,6H2,(H,7,8)

InChIKey

FVTVMQPGKVHSEY-UHFFFAOYSA-N

LogP

-0.04760000000000014

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

118

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

DTXSID60176811
FT-0657756
BRN 2802253
NSC-403362
KBioGR_001312
3-14-00-00843 (Beilstein Handbook Reference)
SB10822
NCGC00024518-03
1-AMINOCYCLOBUTANECARBOXLIC ACID
AKOS005172352
AB00053379-03
SR-01000597721
1-amino-1-cyclobutane carboxylic acid hydrochloride
Tocris-0258
NCGC00024518-01
1-Aminocyclobutanecarboxylic acid
1y1z
HY-30006
ACBC
NSC 403363
22264-50-2
1-Amino-1-cyclobutanecarboxylicacid
SY002606
1K1PGC7J6Z
Q1147632
SR-01000597721-1
KBio3_001546
1-Aminocyclobutanecarboxylicacid
FT-0655686
Spectrum2_001476
AC-5714

MDL Number

MFCD00661068

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 1-Aminocyclobutanecarboxylic acid (CAS: 22264-50-2)?

1-Aminocyclobutanecarboxylic acid is a colorless crystalline solid with a molecular weight of approximately 113.12 g/mol. It has a pKa of about 6.4 and is slightly soluble in water. The compound exhibits moderate reactivity, particularly towards carbonyl compounds. It is used in various chemical reactions due to its amine and carboxylic acid functionalities.

How is 1-Aminocyclobutanecarboxylic acid (CAS: 22264-50-2) typically synthesized?

1-Aminocyclobutanecarboxylic acid can be synthesized via the Mannich reaction, where cyclobutanone, formaldehyde, and an amine are reacted in the presence of an acid catalyst. The reaction provides good selectivity for the target compound with high yield. Other methods include direct amination of cyclobutanecarboxylic acid.

What industries use 1-Aminocyclobutanecarboxylic acid (CAS: 22264-50-2)?

1-Aminocyclobutanecarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of specific polymers, and in the chemical industry for various reactions. It is also used in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 1-Aminocyclobutanecarboxylic acid (CAS: 22264-50-2)?

When handling 1-Aminocyclobutanecarboxylic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, and fume hoods should be used during handling to minimize inhalation risks. In case of spillage, follow the safety data sheet (SDS) guidelines for proper disposal and clean-up procedures.