Compound Q&A

How is 1-Aminocyclobutanecarboxylic acid (CAS: 22264-50-2) typically synthesized?

Answer

1-Aminocyclobutanecarboxylic acid
1-Aminocyclobutanecarboxylic acid can be synthesized via the Mannich reaction, where cyclobutanone, formaldehyde, and an amine are reacted in the presence of an acid catalyst. The reaction provides good selectivity for the target compound with high yield. Other methods include direct amination of cyclobutanecarboxylic acid.

About

CAS No 22264-50-2
English Name 1-Aminocyclobutanecarboxylic acid
Molecular Formula C5H9NO2
Molecular Weight 115.13199999999999 g/mol
SMILES C1CC(C1)(C(=O)O)N
InChIKey FVTVMQPGKVHSEY-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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