9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (1:1) | CAS No. 221352-88-1

9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (1:1)

Basic Information

CAS Number

221352-88-1

Molecular Formula

C19H23ClN2O3

Molecular Weight

362.86 g/mol

AD

Basic Physical Properties

Boiling Point

534.6°C at 760 mmHg

Flash Point

277.1°C

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCN.Cl

InChI

InChI=1S/C19H22N2O3.ClH/c20-9-11-23-12-10-21-19(22)24-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18;/h1-8,18H,9-13,20H2,(H,21,22);1H

InChIKey

ZRXOWZYREIYUHG-UHFFFAOYSA-N

LogP

2.9222000000000006

Topological Polar Surface Area

73.58 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

382

Synonyms & References

English

  • Fmoc-2-(2-aminoethoxy)-ethylamine, HCl
  • (9H-FLUOREN-9-YL)METHYL N-[2-(2-AMINOETHOXY)ETHYL]CARBAMATE HYDROCHLORIDE
  • Fmoc-2-(2-aminoethoxy)ethylamine hydrochloride
  • DTXSID80373305
  • E70579
  • N-Fmoc-2-(2-aminoethoxy)ethanamine HCl
  • AS-72875
  • 221352-88-1
  • 9H-fluoren-9-ylmethyl N-[2-(2-aminoethoxy)ethyl]carbamate;hydrochloride
  • (9H-Fluoren-9-yl)methyl (2-(2-aminoethoxy)ethyl)carbamate hydrochloride
  • MFCD01321025
  • C19H23ClN2O3
  • AKOS015999222
  • (9H-fluoren-9-yl)methyl 2-(2-aminoethoxy)ethylcarbamate hydrochloride
  • Fmoc-2-(2-aminoethoxy)-ethylaminehydrochloride
  • A878686
  • N-Fmoc-2,2'-oxydiethylamine hydrochloride
  • (9H-Fluoren-9-yl)methyl (2-(2-aminoethoxy)-ethyl)carbamate hydrochloride
  • J-014545
  • fmoc-2-(2-aminoethoxy)-ethylamine hydrochloride
  • 2-[2-(Fmoc-amino)ethoxy]ethylamine hydrochloride, >=97.0% (HPLC)
  • (9H-Fluoren-9-yl)methyl (2-(2-aminoethoxy) ethyl)carbamate hydrochloride
  • CS-0204769
  • 2-[2-(Fmoc-amino)ethoxy]ethylamine hydrochloride
  • SCHEMBL5579268
  • (9H-Fluoren-9-yl)methyl [2-(2-aminoethoxy)ethyl]carbamate--hydrogen chloride (1/1)
  • 2-[2-(Fmoc-amino)ethoxy]ethylamine Hydrochloride
  • 9H-fluoren-9-ylmethyl N-[2-(2-aminoethoxy)ethyl]carbamate,hydrochloride
  • Carbamic acid,[2-(2-aminoethoxy)ethyl]-, 9H-fluoren-9-ylmethyl ester, monohydrochloride (9CI)
  • Fmoc-2-(2-aminoethoxy)-ethylamine hydrochloride
  • N-Fmoc-2,2-Oxydiethylamine Hydrochloride

MDL Number

MFCD01321025

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (CAS: 221352-88-1)?

9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride has a crystalline form. Its molecular weight is approximately 406.5 g/mol. It is slightly soluble in water and has good solubility in organic solvents like dichloromethane and acetonitrile. This compound is reactive and can undergo hydrolysis under basic conditions. It has a pKa of around 7.5.

How is 9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (CAS: 221352-88-1) typically synthesized?

9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride is typically synthesized by reacting 9H-fluoren-9-ylmethyl isocyanate with 2-(2-aminoethoxy)ethanol in the presence of a base such as triethylamine. The reaction usually proceeds with high selectivity and decent yield, around 70-80%.

What industries use 9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (CAS: 221352-88-1)?

9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride is used in the pharmaceutical industry for drug synthesis. It also finds applications in polymer chemistry for functionalization and in the semiconductor industry for surface modification. Additionally, it can be used in the development of sensors due to its chemical reactivity.

What precautions should be taken when handling 9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride (CAS: 221352-88-1)?

When handling 9H-Fluoren-9-ylmethyl [2-(2-aminoethoxy)ethyl]carbamate hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and guidance.

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