2-bromopyridine-3-carbonitrile

Basic Information

View in Editor

CAS Number

20577-26-8

Molecular Formula

C6H3BrN2

Molecular Weight

172.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=CC(=C(N=C1)Br)C#N

InChI

InChI=1S/C6H6BrN/c1-5-3-2-4-8-6(5)7/h2-4H,1H3

InChIKey

PZSISEFPCYMBDL-UHFFFAOYSA-N

LogP

2.15252

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

137

Safety Information

View Safety Information

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

20577-26-8
2-Bromo-nicotinonitrile
HMS1655P21
F1957-0002
2-Bromonicotinonitrile
AC-907/25004481
QIPXEPRGYVAQFI-UHFFFAOYSA-N
2-BROMO-3-PYRIDINECARBONITRILE
AB05139
EN300-66595
MFCD00234140
3-Pyridinecarbonitrile, 2-bromo-
W-201793
RB1121
AC-25800
2-bromopyridine-3-carbonitrile
DS-10491
AKOS000320220
SY023829
AM62693
2-BROMO-3-CYANOPYRIDINE
FT-0649121
A814714
DTXSID90355753
SCHEMBL571240
CS-W004810
2-Bromo-3-cyanopyridine
2-BROMO-NICOTINONITRILE
2-Bromo-nicotionitrile
2-Brom-3-cyanpyridin
2-bromonicotinonitrile(SALTDATA: FREE)

MDL Number

MFCD00234140

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8)?

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is a crystalline solid with a molecular weight of 217.04 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react under basic conditions. It has a melting point of around 122-124°C and a boiling point of approximately 285°C. It is used in various chemical syntheses and pharmaceutical applications.

How is 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8) typically synthesized?

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is typically synthesized through the reaction of 2-bromopyridine with hydrogen cyanide. Commonly, this is done using a catalytic hydrogenation process in the presence of a palladium catalyst. The reaction is carried out under pressure and at elevated temperatures to ensure high yield and selectivity. The product can also be obtained by electrophilic aromatic substitution reactions.

What industries use 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8)?

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also used in the polymer industry for the development of novel materials with specific properties. Additionally, it has applications in the field of sensors and as a precursor in semiconductor manufacturing processes.

What precautions should be taken when handling 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8)?

When handling 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Proper storage in a cool, dry place away from direct sunlight is recommended. In case of spills, use appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal. Always refer to the latest SDS for specific handling and storage instructions.