Compound Q&A

How is 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8) typically synthesized?

Answer

2-bromopyridine-3-carbonitrile
2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is typically synthesized through the reaction of 2-bromopyridine with hydrogen cyanide. Commonly, this is done using a catalytic hydrogenation process in the presence of a palladium catalyst. The reaction is carried out under pressure and at elevated temperatures to ensure high yield and selectivity. The product can also be obtained by electrophilic aromatic substitution reactions.

About

CAS No 20577-26-8
English Name 2-bromopyridine-3-carbonitrile
Molecular Formula C6H3BrN2
Molecular Weight 172.03 g/mol
SMILES C1=CC(=C(N=C1)Br)C#N
InChIKey PZSISEFPCYMBDL-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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