2-bromopyridine-3-carbonitrile(CAS: 20577-26-8)

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is a crystalline solid with a molecular weight of 217.04 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react under basic conditions. It has a melting point of around 122-124°C and a boiling point of approximately 285°C. It is used in various chemical syntheses and pharmaceutical applications.

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is typically synthesized through the reaction of 2-bromopyridine with hydrogen cyanide. Commonly, this is done using a catalytic hydrogenation process in the presence of a palladium catalyst. The reaction is carried out under pressure and at elevated temperatures to ensure high yield and selectivity. The product can also be obtained by electrophilic aromatic substitution reactions.

2-Bromopyridine-3-carbonitrile (CAS: 20577-26-8) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also used in the polymer industry for the development of novel materials with specific properties. Additionally, it has applications in the field of sensors and as a precursor in semiconductor manufacturing processes.

When handling 2-bromopyridine-3-carbonitrile (CAS: 20577-26-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Proper storage in a cool, dry place away from direct sunlight is recommended. In case of spills, use appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal. Always refer to the latest SDS for specific handling and storage instructions.