JHW 007 Hydrochloride

Basic Information

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CAS Number

202645-74-7

Molecular Formula

C24H30ClF2NO

Molecular Weight

421.96 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCCCN1C2CCC1CC(C2)OC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl

InChI

InChI=1S/C24H29F2NO.ClH/c1-2-3-14-27-21-12-13-22(27)16-23(15-21)28-24(17-4-8-19(25)9-5-17)18-6-10-20(26)11-7-18;/h4-11,21-24H,2-3,12-16H2,1H3;1H/t21-,22+,23+;

InChIKey

RHYMGBAYGRUKNZ-QKYUOBHYSA-N

LogP

6.288100000000006

Topological Polar Surface Area

12.47 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

437

Synonyms & References

English

JHW 007 Hydrochloride
(3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2. 1]octane hydrochloride (1:1)
(3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride
JHW007 (hydrochloride)
CS-0027866
AKOS024458110
HY-103425
(1S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane;hydrochloride
202645-74-7
JHW007 hydrochloride

MDL Number

MFCD08276982

FAQ

What are the physical and chemical properties of JHW 007 Hydrochloride (CAS: 202645-74-7)?

JHW 007 Hydrochloride is a crystalline solid with a molecular weight of approximately 383.6 g/mol. It has a high solubility in water and moderate solubility in organic solvents. This compound is relatively stable under normal conditions but reacts with bases to form JHW 007. It has a melting point of about 180-185°C.

How is JHW 007 Hydrochloride (CAS: 202645-74-7) typically synthesized?

JHW 007 Hydrochloride is synthesized via a multi-step process involving the condensation of a substituted phenol and a substituted amine, followed by hydrochloric acid treatment to generate the hydrochloride salt. The reaction typically involves a Lewis acid catalyst and requires controlled temperature and pressure conditions to achieve high selectivity and yield.

What industries use JHW 007 Hydrochloride (CAS: 202645-74-7)?

JHW 007 Hydrochloride is primarily used in the pharmaceutical industry for research purposes. It has also shown potential in the development of novel drug candidates and as a tool compound in chemical biology. Additionally, it may have applications in the production of sensors and semiconductors, although its use in these areas is less common.

What precautions should be taken when handling JHW 007 Hydrochloride (CAS: 202645-74-7)?

When handling JHW 007 Hydrochloride, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly decontaminated. Always consult the Safety Data Sheet (SDS) for detailed safety information.