L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide | CAS No. 197794-83-5
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide
Basic Information
CAS Number
197794-83-5
Molecular Formula
C31H53N9O6
Molecular Weight
647.82 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- GTPL3742
- TFLLR (modifications: C-terminal amide)
- HY-P0226
- CS-6494
- PEPTIDE1{T.F.L.L.R.[am]}$$$$
- 197794-83-5
- CHEMBL4065100
- l-threonyl-l-phenylalanyl-l-leucyl-l-leucyl-l-argininamide
- AC-32571
- (2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
- TFLLR-NH2
- TFLLR-NH2(2TFA)
- L-Argininamide, L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-
- HB2921
- AKOS024456615
- AS-76215
- Thr-Phe-Leu-Leu-Arg-amide
- PAR1-AP
- L-Argininamide,L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-
- (Thr¹)-PAR-1 (1-5) amide (human)
- H-THR-PHE-LEU-LEU-ARG-NH2
- TFLLRamide, (Thr1)-TRAP-5 amide, (Thr1)-PAR-1 (1-5) amide (human)
- PAR-1-AP
- REF DUPL: H-Thr-Phe-Leu-Leu-Arg-NH2
- TFLLR-AMIDE
- THR-PHE-LEU-LEU-ARG-NH2
- (Thr1)-TRAP-5 amide
- HYBRIDE HUMAN-XENOPE
- THROMBIN RECEPTOR (PAR-1), HYBRIDE HUMAN-XENOPE
- TFLLR-NH2 Protease-Activated Receptor 1 (PAR1) Agonist
MDL Number
MFCD03093514
FAQ
What are the physical and chemical properties of L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5)?
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide is a crystalline compound with a molecular weight of approximately 841.6 g/mol. It has a solubility of about 0.01 g/L in water at 25°C. The compound is moderately reactive, showing susceptibility to hydrolysis under basic conditions. It is stable in acidic environments. The compound is insoluble in common organic solvents like ethanol and acetonitrile.
How is L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5) typically synthesized?
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide is typically synthesized through solid-phase peptide synthesis (SPPS). The process involves stepwise coupling of the amino acid building blocks, followed by deprotection and cleavage from the solid support. Commonly used coupling agents include HBTU and HOAt, with a high degree of selectivity and yield. The final step involves the addition of the N~5~-(diaminomethylene)-L-ornithinamide moiety.
What industries use L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5)?
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide is primarily used in the pharmaceutical industry for the development of novel drugs, particularly those targeting specific protein-protein interactions. It is also explored in the sensor technology sector for its potential in biosensing applications.
What precautions should be taken when handling L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5)?
When handling L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbent material and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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