Compound Q&A
How is L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide (CAS: 197794-83-5) typically synthesized?
Answer
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide is typically synthesized through solid-phase peptide synthesis (SPPS). The process involves stepwise coupling of the amino acid building blocks, followed by deprotection and cleavage from the solid support. Commonly used coupling agents include HBTU and HOAt, with a high degree of selectivity and yield. The final step involves the addition of the N~5~-(diaminomethylene)-L-ornithinamide moiety.
About
CAS No
197794-83-5
English Name
L-Threonyl-L-phenylalanyl-L-leucyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithinamide
Molecular Formula
C31H53N9O6
Molecular Weight
647.82 g/mol
SMILES
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)N
InChIKey
ANAMCEKSRDPIPX-GFGQVAFXSA-N
Last Updated: 2025-11-07 12:11
