(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (1:1) | CAS No. 1916569-82-8

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (1:1)

Basic Information

CAS Number

1916569-82-8

Molecular Formula

C8H11BrClNO

Molecular Weight

252.54 g/mol

AD

Basic Physical Properties

c1cc(ccc1[C@H](CO)N)Br.Cl

InChI

InChI=1S/C8H10BrNO.ClH/c9-7-3-1-6(2-4-7)8(10)5-11;/h1-4,8,11H,5,10H2;1H/t8-;/m0./s1

InChIKey

PQQGURGSEYFRCS-QRPNPIFTSA-N

LogP

1.863

Topological Polar Surface Area

46.25 Ų

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

113

Synonyms & References

English

  • (R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride
  • (2R)-2-Amino-2-(4-bromophenyl)ethan-1-ol hydrochloride
  • (2S)-2-AMINO-2-(4-BROMOPHENYL)ETHAN-1-OL HCl
  • PQQGURGSEYFRCS-QRPNPIFTSA-N
  • AX8297077
  • (R)-2-amino-2-(4-bromophenyl)ethan-1-ol HCl salt
  • (2R)-2-AMINO-2-(4-BROMOPHENYL)ETHAN-1-OL HYDROCHLRIDE
  • Benzeneethanol, beta-amino-4-bromo-, hydrochloride (1:1), (betaR)-

MDL Number

MFCD12758092

FAQ

What are the physical and chemical properties of (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (CAS: 1916569-82-8)?

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride is a white crystalline solid with a molecular weight of approximately 260.56 g/mol. It has a pKa of about 1.8 and is highly soluble in water. This compound is less reactive than some other amino compounds and shows good solubility in common organic solvents. It is a chiral compound and its specific reactivity can be influenced by the presence of the amino and bromophenyl groups.

How is (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (CAS: 1916569-82-8) typically synthesized?

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride can be synthesized by several methods, including reduction of 2-bromo-2-(4-bromophenyl)ethanol to the corresponding alcohol followed by reaction with ammonia to form the amino group. The reaction is typically carried out under mild conditions to avoid over-reduction, and the use of a base like sodium hydroxide can improve the yield. The product is then treated with hydrochloric acid to form the hydrochloride salt.

What industries use (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (CAS: 1916569-82-8)?

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride finds applications in various industries, particularly in pharmaceuticals where it can be used as a precursor for drug synthesis. It is also utilized in the production of certain dyes and pigments, and as a reagent in analytical chemistry for developing colorimetric sensors due to its chromogenic properties.

What precautions should be taken when handling (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (CAS: 1916569-82-8)?

When handling (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride, it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or fume hood to minimize inhalation of vapors. Spills should be cleaned up with caution, and the site should be washed down with water. It is advisable to consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.

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