(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (1:1)(CAS: 1916569-82-8)

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride is a white crystalline solid with a molecular weight of approximately 260.56 g/mol. It has a pKa of about 1.8 and is highly soluble in water. This compound is less reactive than some other amino compounds and shows good solubility in common organic solvents. It is a chiral compound and its specific reactivity can be influenced by the presence of the amino and bromophenyl groups.

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride can be synthesized by several methods, including reduction of 2-bromo-2-(4-bromophenyl)ethanol to the corresponding alcohol followed by reaction with ammonia to form the amino group. The reaction is typically carried out under mild conditions to avoid over-reduction, and the use of a base like sodium hydroxide can improve the yield. The product is then treated with hydrochloric acid to form the hydrochloride salt.

(2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride finds applications in various industries, particularly in pharmaceuticals where it can be used as a precursor for drug synthesis. It is also utilized in the production of certain dyes and pigments, and as a reagent in analytical chemistry for developing colorimetric sensors due to its chromogenic properties.

When handling (2R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride, it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or fume hood to minimize inhalation of vapors. Spills should be cleaned up with caution, and the site should be washed down with water. It is advisable to consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.