N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan | CAS No. 18904-53-5
N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan
Basic Information
CAS Number
18904-53-5
Molecular Formula
C24H27N3O5
Molecular Weight
437.5 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- CHEMBL1592072
- (2S)-2-[(2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-3-METHYLBUTANAMIDO]-3-(1H-INDOL-3-YL)PROPANOIC ACID
- MLS001243453
- BS-27397
- (2S)-3-(1H-indol-3-yl)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoic acid
- MFCD00238521
- HMS2211I16
- (S)-2-((S)-2-(benzyloxycarbonylamino)-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid
- 18904-53-5
- Z-VAL-TRP-OH
- SMR000841577
- L-Tryptophan,N-[(phenylmethoxy)carbonyl]-L-valyl- (9CI)
- Z-val-trp-oh
- Z-VAL-TRP-OME
- 3,4-DEHYDRO-L-PROLINE AMIDE HYDROCHLORIDE
- 3,4-DEHYDRO-PROLINE-NH2 HCL
- H-3,4-Dehydro-Pro-NH2
- H-DEHYDROPRO-NH2 HCL
- L-3,4-dehydroprolinamide hydrochloride
- Z-Val-Trp-OH99%
MDL Number
MFCD00238521
FAQ
What are the physical and chemical properties of N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan (CAS: 18904-53-5)?
N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan has a white crystalline form. Its molecular weight is approximately 467.48 g/mol. It is moderately soluble in water and organic solvents. It is known for its reactivity towards nucleophiles and its stability under acidic conditions. This compound is used in peptide synthesis and pharmaceutical research.
How is N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan (CAS: 18904-53-5) typically synthesized?
N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan is typically synthesized through solid-phase peptide synthesis. The key steps involve the coupling of valine and tryptophan with a benzyloxycarbonyl (Boc) protecting group, followed by deprotection of the Boc group. Commonly used catalysts include DIC and HOBT. The yield is usually around 70-80%. This method allows for controlled synthesis and high purity.
What industries use N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan (CAS: 18904-53-5)?
N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan is primarily used in the pharmaceutical and biotechnology industries due to its importance in peptide and drug synthesis. It is also relevant in the development of new biomolecules and in research for potential therapeutic applications.
What precautions should be taken when handling N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan (CAS: 18904-53-5)?
When handling N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. If a spill occurs, it should be immediately cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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