Compound Q&A

How is N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan (CAS: 18904-53-5) typically synthesized?

Answer

N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan
N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan is typically synthesized through solid-phase peptide synthesis. The key steps involve the coupling of valine and tryptophan with a benzyloxycarbonyl (Boc) protecting group, followed by deprotection of the Boc group. Commonly used catalysts include DIC and HOBT. The yield is usually around 70-80%. This method allows for controlled synthesis and high purity.

About

CAS No 18904-53-5
English Name N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan
Molecular Formula C24H27N3O5
Molecular Weight 437.5 g/mol
SMILES CC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)OCC3=CC=CC=C3
InChIKey OFRAUBNHWUYJIM-SFTDATJTSA-N
Last Updated: 2026-01-13 15:28

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