N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan(CAS: 18904-53-5)

N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan has a white crystalline form. Its molecular weight is approximately 467.48 g/mol. It is moderately soluble in water and organic solvents. It is known for its reactivity towards nucleophiles and its stability under acidic conditions. This compound is used in peptide synthesis and pharmaceutical research.

N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan is typically synthesized through solid-phase peptide synthesis. The key steps involve the coupling of valine and tryptophan with a benzyloxycarbonyl (Boc) protecting group, followed by deprotection of the Boc group. Commonly used catalysts include DIC and HOBT. The yield is usually around 70-80%. This method allows for controlled synthesis and high purity.

N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan is primarily used in the pharmaceutical and biotechnology industries due to its importance in peptide and drug synthesis. It is also relevant in the development of new biomolecules and in research for potential therapeutic applications.

When handling N-[(Benzyloxy)carbonyl]-L-valyl-L-tryptophan, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. If a spill occurs, it should be immediately cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.