Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride)

Basic Information

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CAS Number

1871-76-7

Molecular Formula

C14H11ClO

Molecular Weight

230.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

49-53 °C

Boiling Point

175-176 °C/17 mmHg

Refractive Index

1.5260 (estimate)

SMILES

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C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)Cl

InChI

InChI=1S/C14H11ClO/c15-14(16)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13H

InChIKey

MSYLETHDEIJMAF-UHFFFAOYSA-N

LogP

3.5839000000000016

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

209

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

Diphenylacetyl chloride
2,2-Diphenylacetyl chloride
SY049536
6553C1CB9S
Q-201007
BRN 1211588
diphenyl-acetyl chloride
Diphenylacetic acid chloride
DIPHENYLACETIC ACID ACID CHLORIDE [MI]
NSC-120906
SCHEMBL237104
FT-0625251
Diphenylacetyl chloride, 90%, technical grade
2,2-diphenylacetic acid chloride
1871-76-7
.ALPHA.-PHENYLBENZENEACETYL CHLORIDE
2,2-diphenyl-acetyl chloride
AS-15886
A813123
Benzeneacetyl chloride, .alpha.-phenyl-
Acetyl chloride, diphenyl-
.alpha.,.alpha.-Diphenylacetyl chloride
GEO-02786
UNII-6553C1CB9S
Diphenylacetylchloride
2,2-diphenylacetylchloride
D2763
AKOS015889497
EINECS 217-493-5
diphenyl acetyl chloride
Q27263827

MDL Number

MFCD00013655

Customs Code

29163900

FAQ

What are the physical and chemical properties of Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride) (CAS: 1871-76-7)?

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) is a crystalline solid with a molecular weight of approximately 277.24 g/mol. It is soluble in organic solvents such as ethanol and acetone. This compound exhibits limited reactivity, primarily through electrophilic aromatic substitution and acyl chloride addition reactions.

How is Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride) (CAS: 1871-76-7) typically synthesized?

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) can be synthesized by reacting diphenylacetyl chloride with adipic acid. The reaction typically involves heating the mixture in the presence of a catalyst such as p-toluenesulfonic acid to achieve a yield of around 75-80%. The product is then purified by recrystallization.

What industries use Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride) (CAS: 1871-76-7)?

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) is primarily used in pharmaceuticals and organic synthesis. It plays a role in the production of intermediates for drug synthesis and as a reagent in various organic reactions. Its use in polymer synthesis and sensors is also reported, though it is not a primary component.

What precautions should be taken when handling Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride) (CAS: 1871-76-7)?

When handling Adiphenine HCl Impurity 1 (CAS: 1871-76-7), ensure the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, clean up using appropriate procedures and consult the Safety Data Sheet (SDS) for specific guidelines. Work in a well-ventilated area or a fume hood to avoid inhalation exposure.