Adiphenine HCl Impurity 1 (2,2-Diphenylacetyl chloride)(CAS: 1871-76-7)

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) is a crystalline solid with a molecular weight of approximately 277.24 g/mol. It is soluble in organic solvents such as ethanol and acetone. This compound exhibits limited reactivity, primarily through electrophilic aromatic substitution and acyl chloride addition reactions.

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) can be synthesized by reacting diphenylacetyl chloride with adipic acid. The reaction typically involves heating the mixture in the presence of a catalyst such as p-toluenesulfonic acid to achieve a yield of around 75-80%. The product is then purified by recrystallization.

Adiphenine HCl Impurity 1 (CAS: 1871-76-7) is primarily used in pharmaceuticals and organic synthesis. It plays a role in the production of intermediates for drug synthesis and as a reagent in various organic reactions. Its use in polymer synthesis and sensors is also reported, though it is not a primary component.

When handling Adiphenine HCl Impurity 1 (CAS: 1871-76-7), ensure the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, clean up using appropriate procedures and consult the Safety Data Sheet (SDS) for specific guidelines. Work in a well-ventilated area or a fume hood to avoid inhalation exposure.