(E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate | CAS No. 18474-55-0
(E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate
Basic Information
CAS Number
18474-55-0
Molecular Formula
C11H13BrN2O2
Molecular Weight
285.14 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- ethyl (E)-2-(2-(2-bromophenyl)hydrazono)propanoate
- Ethyl (2Z)-2-[(2-bromophenyl)hydrazinylidene]propanoate
- (E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate
- 18474-55-0
- Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate
- (E)-Ethyl 2-(2-(2-bromophenyl)hydrazo)propaate
- 2-(2-bromo-phenylhydrazono)-propionic acid ethyl ester
- 2-(2-Bromphenyl)-1,3-indandion
- 2-(2-Brom-phenyl)-1,3-indandion
- 2-(2-Brom-phenyl)-indan-1,3-dion
- 2-(2-Brom-phenylhydrazono)-propionsaeure-aethylester
- 2-(o-bromphenyl)-indandion-1,3
- AC1MBW7N
- Brenztraubensaeureethylester-(2-brom-phenylhydrazon)
- CTK4C5232
- HMS1447B01
- Maybridge3_005655
- Oprea1_248831
- Pyruvinsaeure-(o-brom-phenylhydrazon)-ethylester
MDL Number
MFCD11053776
Customs Code
2928000090
FAQ
What are the physical and chemical properties of (E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate (CAS: 18474-55-0)?
(E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate is a crystalline solid with a molecular weight of approximately 357.04 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. The compound exhibits limited reactivity, primarily due to the bromine substituent, which affects its stability and reactivity in aqueous environments.
How is (E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate (CAS: 18474-55-0) typically synthesized?
(E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate is synthesized via a hydrazination reaction of ethyl malonate with 2-bromophenylhydrazine. The reaction typically occurs in the presence of a mild base like potassium carbonate and is performed at room temperature. The yield is generally between 70-80%, with high selectivity towards the E-isomer.
What industries use (E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate (CAS: 18474-55-0)?
(E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate is used in the pharmaceutical industry for the synthesis of certain anti-inflammatory and antiparasitic drugs. It is also explored in polymer production for its potential as a stabilizer. Additionally, it may be used in the development of sensors and as a reagent in analytical chemistry.
What precautions should be taken when handling (E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate (CAS: 18474-55-0)?
When handling (E)-Ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or in a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be ventilated thoroughly. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures and storage guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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