4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride | CAS No. 184475-70-5
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
Basic Information
CAS Number
184475-70-5
Molecular Formula
C17H14Cl2FN3O3
Molecular Weight
398.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- FT-0651490
- RBFWFFFXYPQXHG-UHFFFAOYSA-N
- CL3494
- AKOS015888616
- Methyl (S)-N-(tert-butoxycarbonyl)pyroglutamate
- 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl acetate hydrochloride (1:1)
- 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazo-lin-6-yl acetate hydrochloride
- AC-8514
- DTXSID20625991
- 184475-70-5
- 4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl acetate--hydrogen chloride (1/1)
- SCHEMBL641764
- 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetatehydrochloride
- J-513373
- 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate hydrochloride
- A812871
- 6-Acetoxy-4-(3-chloro-4-fluoroanilino)-7-methoxyquinazoline hydrochloride
- 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
- [4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl] acetate;hydrochloride
- 4-(3-chloro-4-fluorophenylaMino)-7-Methoxyquinazol
- 4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate HCl
- 6-acetoxy-4-(3'-chloro-4'-fluoroanilino)-7-Methoxyquinazolinehydrochloridesalt
- 4-(3-chloro-4-fluorophenylaMino)-6-Acetoxy -7-Methoxyquinazoline Hydrochloride
MDL Number
MFCD12761612
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride (CAS: 184475-70-5)?
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride is a crystalline solid with a molecular weight of approximately 433.68 g/mol. It has a solubility of about 100 mg/mL in water and moderate solubility in organic solvents. It is highly reactive towards nucleophiles and can undergo substitution reactions. The compound is stable under normal conditions but should be stored at room temperature away from direct sunlight.
How is 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride (CAS: 184475-70-5) typically synthesized?
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride is typically synthesized via a multi-step process involving the condensation of 7-methoxyquinazoline-6-carbaldehyde with 3-chloro-4-fluoroaniline, followed by acetylation and hydrochloride formation. The synthesis involves the use of catalysts such as piperidine and requires careful control of reaction conditions to achieve high yield and selectivity.
What industries use 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride (CAS: 184475-70-5)?
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride is primarily used in the pharmaceutical industry for its potential in developing new therapeutic agents. It may also find applications in sensor technology, where its chemical reactivity and stability make it suitable for detecting specific analytes. Additionally, it could have potential uses in the semiconductor industry for its electronic properties.
What precautions should be taken when handling 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride (CAS: 184475-70-5)?
When handling 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up using appropriate spill control measures, and the area should be thoroughly rinsed. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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