7,10-Dimethoxy-10-DAB III

Basic Information

View in Editor

CAS Number

183133-94-0

Molecular Formula

C31H40O10

Molecular Weight

572.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)OC)C)OC

InChI

InChI=1S/C31H40O10/c1-16-19(33)14-31(36)26(40-27(35)18-11-9-8-10-12-18)24-29(5,25(34)23(38-7)22(16)28(31,3)4)20(37-6)13-21-30(24,15-39-21)41-17(2)32/h8-12,19-21,23-24,26,33,36H,13-15H2,1-7H3/t19-,20-,21+,23+,24-,26-,29+,30-,31+/m0/s1

InChIKey

MGJMLMORVVDLIU-VHLOTGQHSA-N

LogP

2.3900000000000006

Complexity

1120

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

10-Deacetyl-7,10-dimethoxy-Baccatin III
7,10-Dimethoxy-10-DAB III
7,10-MeO-10-DAB
7β,10β-DiMethoxy-10-dabⅢ
7,10-dimethyl-10-DAB
7,10-dimethylbaccatin III
7β,10β-dimethoxy-10-DAB-III
7β,10β-dimethoxy-10-deacetylbaccatin III
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
Cabazitaxel IMP
Cabazitaxel Impurity
Cabazitaxel Impurity 1
Cabazitaxel Impurity 2
Cabazitaxel Impurity 3
Cabazitaxel Impurity 4
Cabazitaxel Impurity 5
Cabazitaxel Impurity 6
Cabazitaxel Impurity 7
BCP06123
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12
10-Deacetyl-7,10-dimethoxy-baccatin III
SCHEMBL7509209
7,10-Dimethoxy-10-DABIII
EX-A3599
MFCD23100710
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(ACETYLOXY)-1,15-DIHYDROXY-9,12-DIMETHOXY-10,14,17,17-TETRAMETHYL-11-OXO-6-OXATETRACYCLO[11.3.1.0(3),(1)?.0?,?]HEPTADEC-13-EN-2-YL BENZOATE
CS-0022604
DTXSID301098192
F12858
AC-27007
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,15-dihydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

MDL Number

MFCD23100710

FAQ

What are the physical and chemical properties of 7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0)?

7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0) is a solid with a crystalline form. Its molecular weight is approximately 254.23 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. Chemically, it is less reactive due to the presence of methoxy substituents, which make it less prone to further oxidation or reduction reactions.

How is 7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0) typically synthesized?

7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0) can be synthesized through the methylation of 10-DAB III with methanol in the presence of a strong acid catalyst like hydrochloric acid. The reaction proceeds with high selectivity, yielding a high yield of the desired product.

What industries use 7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0)?

7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0) is primarily used in the pharmaceutical and polymer industries. It can be incorporated into polymers to enhance their properties or used as a precursor in the synthesis of pharmaceutical compounds.

What precautions should be taken when handling 7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0)?

When handling 7,10-Dimethoxy-10-DAB III (CAS: 183133-94-0), one should use appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up with the appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for more detailed handling information.