7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine | CAS No. 179552-73-9

7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine

Basic Information

CAS Number

179552-73-9

Molecular Formula

C14H7Cl2FN4O2

Molecular Weight

353.14 g/mol

AD

Basic Physical Properties

Boiling Point

503.3±50.0°C at 760 mmHg

C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])Cl)Cl)F

InChI

InChI=1S/C14H7Cl2FN4O2/c15-9-3-7(1-2-11(9)17)20-14-8-4-13(21(22)23)10(16)5-12(8)18-6-19-14/h1-6H,(H,18,19,20)

InChIKey

ALJPGKSDBZFNBR-UHFFFAOYSA-N

Complexity

442

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 7-chloro-n-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine
  • 4-(3-Chloro-4-fluoro phenylamino)-7-chloro-6-nitro-quinazoline
  • N-(3-Chloro-4-fluorophenyl)-7-chloro-6-nitro-4-quinazolinaMine
  • 7-Chloro-N-(3-chloro-4-fluorophenyl)-6-nitro-4-quinazolinamine
  • ALJPGKSDBZFNBR-UHFFFAOYSA-N
  • C14H7Cl2FN4O2
  • BCP08724
  • SB00004
  • AK173030
  • Y1297
  • (7-chloro-6-nitro-4-quinazolinyl)-(3-chloro-4-fluorophenyl)amine
  • 4-Quinazolinamine, 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitro-
  • 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine
  • AC-25021
  • H11167
  • DTXSID70618752
  • SCHEMBL1366535
  • MFCD19440823
  • CS-0157049
  • ES-2010
  • AMY19322
  • A854958
  • AKOS025395808
  • 179552-73-9
  • 4-(3-CHLORO-4-FLUORO PHENYLAMINO)-7-CHLORO-6-NITRO-QUINAZOLINE
  • NS00008907
  • DB-129606
  • SY120895
  • EC 810-185-7

MDL Number

MFCD19440823

FAQ

What regulatory guidelines apply to 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine (CAS: 179552-73-9)?

The compound 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine is subject to various regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA requirements. GHS provides specific criteria for hazard communication, including safety data sheets and label elements. REACH regulations require pre-market registration of the substance, including information on its production quantities, use, and potential environmental and health effects. FDA and EPA regulations may also apply based on the intended use of the compound, such as pharmaceutical or agricultural applications.

Are there alternatives to 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine in synthesis?

There are several alternatives to 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine in synthesis. For instance, using different functional groups or substituents can lead to the formation of similar nitrogen-containing heterocycles. Common alternative reagents include various aromatics, nitriles, or diazonium salts. These alternatives can offer similar reactivity profiles but with different synthetic pathways and possibly improved safety profiles.

What is the market or research trend for 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine?

The research and market trends for 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine indicate increasing interest in its potential applications in medicinal chemistry and synthetic biology. The compound is often studied for its biological activity, particularly in the development of novel pharmaceuticals. Market trends suggest a growing emphasis on optimizing synthesis methods and improving the compound’s therapeutic potential. Additionally, research is focusing on its role in exploring new drug targets and understanding its biochemical interactions.

How should waste containing 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine be handled?

Waste containing 7-chloro-N-(3-chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine should be handled according to stringent safety protocols. Waste collection should be conducted in lined and sealed containers to prevent environmental contamination. Proper incineration or professional waste disposal methods should be employed, ensuring compliance with local and international regulations. Environmental protection precautions include minimizing exposure to air, water, and soil. Appropriate personal protective equipment (PPE) should be worn during handling, and waste disposal should follow recommended guidelines to ensure safety and environmental protection.

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