Decarboxyl ofloxacin, (S)-

Basic Information

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CAS Number

178964-53-9

Molecular Formula

C17H20FN3O2

Molecular Weight

317.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

154-158°C

SMILES

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CC1COC2=C3N1C=CC(=O)C3=CC(=C2N4CCN(CC4)C)F

InChI

InChI=1S/C17H20FN3O2/c1-11-10-23-17-15-12(14(22)3-4-21(11)15)9-13(18)16(17)20-7-5-19(2)6-8-20/h3-4,9,11H,5-8,10H2,1-2H3/t11-/m0/s1

InChIKey

XTLCAWXSWVQNHK-NSHDSACASA-N

LogP

1.8457999999999999

Topological Polar Surface Area

37.71 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

506

Synonyms & References

English

Descarboxyl Levofloxacin
(S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one hydrochloride
Levofloacin Impurity 28
Levofloxacin Descarboxy IMpurity
Descarboxyl Levofloxacin IMpurity
(S)-Ofloxacin EP Impurity B (Decarboxyl Levofloxacin)
(S)-9-fluoro-3-methyl-10- (4-methylpiperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine
(S)-decarboxyl ofloxacin
(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2H-[1,4]oxazino[2,3,4-ij]quinolin-7(3H)-one
BS-44655
(3S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-pyrido(1,2,3-de)-1,4-benzoxazin-7-one
Q27253486
A1-01734
20TYA9K7RU
Decarboxyl ofloxacin, (S)-
LEVOFLOXACIN HEMIHYDRATE IMPURITY E [EP IMPURITY]
(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one
DTXSID50170621
F19367
7H-Pyrido(1,2,3-de)-1,4-benzoxazin-7-one, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-, (3S)-
178964-53-9
(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraen-10-one
UNII-20TYA9K7RU
DescarboxylLevofloxacin
(S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one

MDL Number

MFCD28016445

FAQ

What are the physical and chemical properties of Decarboxyl ofloxacin (CAS: 178964-53-9)?

Decarboxyl ofloxacin (CAS: 178964-53-9) is a crystalline compound with a molecular weight of approximately 423.44 g/mol. It has a high solubility in water and moderate solubility in organic solvents. The compound is relatively stable under normal conditions but can degrade upon exposure to light and heat. It reacts readily with bases to form the corresponding salts.

How is Decarboxyl ofloxacin (CAS: 178964-53-9) typically synthesized?

Decarboxyl ofloxacin (CAS: 178964-53-9) is synthesized by decarboxylation of ofloxacin under mild basic conditions in the presence of a catalyst such as potassium carbonate. The reaction is conducted in an organic solvent like acetonitrile, and the product is isolated by filtration and recrystallization.

What industries use Decarboxyl ofloxacin (CAS: 178964-53-9)?

Decarboxyl ofloxacin (CAS: 178964-53-9) is primarily used in the pharmaceutical industry for the development of new antibiotics. It also has applications in the polymer industry as a stabilizer and in the production of semiconductors due to its electronic properties.

What precautions should be taken when handling Decarboxyl ofloxacin (CAS: 178964-53-9)?

When handling Decarboxyl ofloxacin (CAS: 178964-53-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from direct sunlight. In case of spill, it should be handled in a fume hood and cleaned up using standard procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.