Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate | CAS No. 1715-33-9

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate

Basic Information

CAS Number

1715-33-9

Molecular Formula

C25H31NaO8

Molecular Weight

482.5 g/mol

AD

Basic Physical Properties

Boiling Point

689.8°C at 760 mmHg

Density

1.359

Flash Point

233.528°C

Refractive Index

1.6

CC12CC(C3C(C1CCC2(C(=O)COC(=O)CCC(=O)[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+]

InChI

InChI=1S/C25H32O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChIKey

FKKAEMQFOIDZNY-CODXZCKSSA-M

LogP

0.63860

Complexity

957

Synonyms & References

English

  • PREDNISOLONE SODIUM SUCCINATE [WHO-DD]
  • PREDNISOLONE SODIUM SUCCINATE [MART.]
  • PREDNISOLONE SODIUM SUCCINATE (USP IMPURITY)
  • PREDNISOLONE 21-SUCCINATE SODIUM SALT [MI]
  • 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(sodium succinate)
  • PREDNISOLONE SODIUM SUCCINATE [USP IMPURITY]
  • DTXSID8023503
  • Prednisolone sodium succinate, injection
  • Predonine soluble
  • MLS001424152
  • Prednisolone 21-succinate sodium
  • Prednisolone sodium hemisuccinate
  • Prednisolone sodium succinate [USP:JAN]
  • CCG-101061
  • Solu-Delta Cortef Sterile Powder
  • NC00311
  • NSC-9151
  • Q27269293
  • DTXCID503503
  • Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-(hydrogen succinate), monosodium salt
  • Prednisolone 21-hemisuccinate sodium
  • UNII-8223RR9DWF
  • SCHEMBL122046
  • sodium 4-((11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl)oxy)-4-oxobutanoate
  • EINECS 216-995-1
  • Sodium prednisolone 21-hemisuccinate
  • PREDNISOLONE SODIUM SUCCINATE (MART.)
  • Solu-Decortin
  • Methyprednisolone sodium succinate
  • HMS2051N20
  • Precortalon Aquosum

MDL Number

MFCD00273263

FAQ

What are the physical and chemical properties of Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate (CAS: 1715-33-9)?

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is an organic compound. It crystallizes as colorless needles or white powder. The molecular weight is approximately 536.47 g/mol. It is slightly soluble in water but soluble in ethanol. This compound is reactive towards bases and hydrolysis under basic conditions. It is also prone to oxidation.

How is Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate (CAS: 1715-33-9) typically synthesized?

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is synthesized via a multi-step process involving the reaction of progesterone and sodium hydroxide in a basic medium followed by esterification. Common catalysts include sodium hydride. The yield is around 85%, and selectivity is high for the desired product.

What industries use Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate (CAS: 1715-33-9)?

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is used primarily in the pharmaceutical industry as an intermediate for hormone-based drugs. It is also used in the research of hormone-related treatments and may have applications in the polymer and sensor industries.

What precautions should be taken when handling Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate (CAS: 1715-33-9)?

When handling Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a chemical fume hood to minimize exposure. In case of spill, immediately clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for detailed instructions. Avoid contact with eyes, skin, and inhalation. Dispose of waste according to local regulations.

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