Compound Q&A
How is Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate (CAS: 1715-33-9) typically synthesized?
Answer
![Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate](https://static.chemtradehub.com/structs/171/1715-33-9-b9b4.webp "Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate")
Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is synthesized via a multi-step process involving the reaction of progesterone and sodium hydroxide in a basic medium followed by esterification. Common catalysts include sodium hydride. The yield is around 85%, and selectivity is high for the desired product.
About
CAS No
1715-33-9
English Name
Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate
Molecular Formula
C25H31NaO8
Molecular Weight
482.5 g/mol
SMILES
CC12CC(C3C(C1CCC2(C(=O)COC(=O)CCC(=O)[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+]
InChIKey
FKKAEMQFOIDZNY-CODXZCKSSA-M
Last Updated: 2025-12-29 01:16
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