Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate(CAS: 1715-33-9)

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is an organic compound. It crystallizes as colorless needles or white powder. The molecular weight is approximately 536.47 g/mol. It is slightly soluble in water but soluble in ethanol. This compound is reactive towards bases and hydrolysis under basic conditions. It is also prone to oxidation.

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is synthesized via a multi-step process involving the reaction of progesterone and sodium hydroxide in a basic medium followed by esterification. Common catalysts include sodium hydride. The yield is around 85%, and selectivity is high for the desired product.

Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate is used primarily in the pharmaceutical industry as an intermediate for hormone-based drugs. It is also used in the research of hormone-related treatments and may have applications in the polymer and sensor industries.

When handling Sodium 4-{[(11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoate, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a chemical fume hood to minimize exposure. In case of spill, immediately clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for detailed instructions. Avoid contact with eyes, skin, and inhalation. Dispose of waste according to local regulations.