Selamectin | CAS No. 165108-07-6

Selamectin

Basic Information

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CAS Number

165108-07-6

Molecular Formula

C43H63NO11

Molecular Weight

770 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1CCC2(CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5=NO)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)O)OC)C)OC1C7CCCCC7

InChI

InChI=1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1

InChIKey

AFJYYKSVHJGXSN-XHKIUTQPSA-N

Complexity

1550

Synonyms & References

English

SELAMECTIN [USAN]
Tox21_111408
Selamectin (USAN/INN)
SCHEMBL120105
NCGC00095066-01
Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-
25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a
STRONGHOLD PLUS COMPONENT SELAMECTIN
HY-107212
AVERMECTIN A1A, 25-CYCLOHEXYL-4'-O-DE(2,6-DIDEOXY-3-O-METHYL-alpha-L-ARABINO-HEXOPYRANOSYL)-5-DEMETHOXY-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-5(HYDROXYIMINO)-, (5Z)-
D05813
Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-.alpha.-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-
25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22 23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide
(2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20aR,20bS)-6'-cyclohexyl-7-((2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy)-3',4',5',6,6',7,10,11,14,15,20a,20b-dodecahydro-20b-hydroxy-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17,20(17aH)-dione 20-oxime
Revolt
CAS-165108-07-6
(1R,4S,5'S,6R,6'S,8R,10E,12S,13S,14E,16E,20R,21Z,24S)-6'-cyclohexyl-24-hydroxy-21-hydroxyimino-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
MFCD31621085
SELAMECTIN (USP-RS)
SELAMECTIN (EMA EPAR VETERINARY)
selamectinum
AKOS026749796
EX-A3581
UNII-A2669OWX9N
SELAMECTIN [USP MONOGRAPH]
Selarid
UK 124114
CHEMBL1908325
SELAMECTIN COMPONENT OF STRONGHOLD PLUS
Revolution (antibiotic)
A2669OWX9N

MDL Number

MFCD09837837

FAQ

What are the physical and chemical properties of Selamectin (CAS: 165108-07-6)?

Selamectin is a white to slightly off-white crystalline粉末. Its molecular weight is approximately 426.48 g/mol. Selamectin has low water solubility and is sparingly soluble in organic solvents like ethanol and methanol. It is stable under normal conditions but may react with strong acids or bases. Selamectin is insoluble in water and has good lipophilicity, making it suitable for topical administration.

How is Selamectin (CAS: 165108-07-6) typically synthesized?

Selamectin is typically synthesized through a multistep organic synthesis process involving several key reactions such as alkylation, cyclization, and oxidation. The synthesis employs common organic solvents and requires the use of protecting groups. The overall yield is moderate, and the process involves the use of catalysts and reagents like sodium hydride, dichloromethane, and tert-butanol. The final product is obtained through recrystallization and purification steps.

What industries use Selamectin (CAS: 165108-07-6)?

Selamectin is primarily used in the pharmaceutical industry for its use as a deworming and antiparasitic agent in veterinary medicine. It is also used in the agricultural industry for pest control. Additionally, it has potential applications in the medical field for treating parasitic infections in humans. While not extensively studied, there is interest in using Selamectin in sensor development due to its unique chemical properties.

What precautions should be taken when handling Selamectin (CAS: 165108-07-6)?

When handling Selamectin, it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials and disposing of the waste according to local regulations. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures. Selamectin is not known to be highly reactive, but care should be taken to avoid contact with strong acids or bases.