1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide | CAS No. 1646818-35-0

1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide

Basic Information

CAS Number

1646818-35-0

Molecular Formula

C313C5H12N4O5

Molecular Weight

249.17 g/mol

AD

Basic Physical Properties

NC(=O)C1N=CN(N=1)[13C@@H]1O[13CH]([13CH2]O)[13C@@H](O)[13C@H]1O

InChI

InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3?,4-,5-,8-/m1/s1/i1+1,3+1,4+1,5+1,8+1

InChIKey

IWUCXVSUMQZMFG-IWNSTHTFSA-N

LogP

-3.0114999999999994

Topological Polar Surface Area

143.72000000000003 Ų

Hydrogen Bond Donor/Acceptor

5 / 9

Synonyms & References

English

  • Ribavirin-13C5

MDL Number

MFCD09841249

FAQ

What are the physical and chemical properties of 1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide (CAS: 1646818-35-0)?

This compound is a crystalline solid with a molecular weight of approximately 329.23 g/mol. It is slightly soluble in water and organic solvents. Chemically, it is reactive towards nucleophiles and exhibits good stability under neutral conditions. It has limited solubility in common solvents, making it suitable for applications requiring controlled reactivity.

How is 1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide (CAS: 1646818-35-0) typically synthesized?

This compound is synthesized via a multi-step process involving the protection of the sugar moiety, followed by the introduction of the triazole ring and amide functional group. Common catalysts used include palladium and copper complexes. The final product is obtained with high selectivity and yield, typically around 80%.

What industries use 1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide (CAS: 1646818-35-0)?

This compound is primarily used in the pharmaceutical industry for its potential as a drug candidate, particularly in antiviral and anticancer research. It is also explored for its use in sensor technology and as a building block in polymer synthesis.

What precautions should be taken when handling 1-[(4xi)-beta-D-(~13~C_5_)-erythro-Pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide (CAS: 1646818-35-0)?

When handling this compound, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.

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