10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl)- | CAS No. 161696-76-0
10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl)-
Basic Information
CAS Number
161696-76-0
Molecular Formula
C16H18N4S
Molecular Weight
298.4 g/mol
AD
Basic Physical Properties
Melting Point
144.5°C
Safety Information
View Safety InformationHazard Statement
H225
Highly Flammable liquid and vapor
Flammable liquids
Flammable liquids
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
Synonyms & References
English
- 2-methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzo diazepine
- N-Desmethylolanzapine, 1mg/ml in Acetonitrile
- 4-DESMETHYLOLANZAPINE
- CHEBI:168745
- FT-0665713
- N-Desmethylolanzapine; Desmethylolanzapine; 2-Methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine; 4'-Desmethylolanzapine; LY 170055; N-Demethylolanzapine
- 4'-N-desmethyl olanzapine
- CHEMBL1125
- N-Demethylolanzapine
- MFCD09840321
- LY-170055
- HY-W009247
- olanzapine, N-desmethyl
- FHPIXVHJEIZKJW-UHFFFAOYSA-N
- 4'-Desmethylolanzapine
- N-Desmethylolanzapine
- F19399
- CS-W009963
- DESMETHYLOLANZAPINE
- UNII-C1053I7P65
- N-desmethyl-olanzapine
- N-Demethyl Olanzapine
- MS-20583
- AKOS015914078
- J-009851
- 2-methyl-4-piperazin-1-yl-10h-thieno[2,3-b][1,5]benzodiazepine
- Q27275031
- 2-methyl-4-piperazin-1-yl-5H-thieno[3,2-c][1,5]benzodiazepine
- DTXSID30433226
- BDBM50240701
- 2-Methyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-benzo[f]azulene
MDL Number
MFCD09840321
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0)?
10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0) has a crystalline form with a molecular weight of approximately 363.46 g/mol. It is slightly soluble in water but soluble in organic solvents such as ethanol and dioxane. The compound is relatively stable under normal conditions but may react with strong acids or bases. It has a melting point of around 150-152°C.
How is 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0) typically synthesized?
10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0) is typically synthesized via multistep organic synthesis involving Friedel-Crafts alkylation and amination reactions. The synthesis involves the use of 2-methyl-4-piperidone as the starting material, which undergoes a series of transformations to achieve the desired product. The reaction conditions and catalysts are optimized for high selectivity and yield.
What industries use 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0)?
10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0) is primarily used in the pharmaceutical industry due to its potential as an anticonvulsant and anxiolytic agent. It is also explored in the polymer industry for its potential as a stabilizer or additive. Additionally, it may find applications in the development of sensors and as a precursor in semiconductor manufacturing.
What precautions should be taken when handling 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0)?
When handling 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl) (CAS: 161696-76-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. A Material Safety Data Sheet (MSDS) should be consulted for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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