3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid

Basic Information

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CAS Number

16052-06-5

Molecular Formula

C9H20N2O4S

Molecular Weight

252.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

237-239 °C

Water Solubility

Soluble in water. 25.2 g/L (20°C)

Solubility

H2O: 1 M at 20 °C, clear, colorless

Refractive Index

1.6800 (estimate)

SMILES

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C1CN(CCN1CCCS(=O)(=O)O)CCO

InChI

InChI=1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)

InChIKey

OWXMKDGYPWMGEB-UHFFFAOYSA-N

LogP

-1.1257999999999975

pKa

8.0(at 25℃)

Topological Polar Surface Area

81.08000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

280

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

light-sensitive

Synonyms & References

English

CS-0015183
N-(2-Hydroxyethyl)piperazine-N'-(3-propanesulfonic acid)
EP1
AC-24630
Q1563525
4-(2-Hydroxyethyl)-1-piperazinepropanesulphonic acid
PD080191
EPPS, BioXtra, >=99.5% (titration)
N-2-Hydroxyethylpiperazine-N-3-propanesulfonic acid
EPPS, BioPerformance Certified, cell culture tested, >=99.5% (titration)
3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid
3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonicAcid
AS-69273
SCHEMBL98490
MFCD12546632
N-(Hydroxyethyl)piperazine-N'-propane sulfonic acid
4-(2-Hydroxyethyl)piperazine-1-propane-3-sulfonic acid
BRN 3957385
4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid
3-(4-(2-hydroxyethyl)piperazinyl)propanesulfonic acid (HEPPS)
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid
CHEBI:42298
8JN5PQW99C
UNII-8JN5PQW99C
A810147
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid #
EPPS, Vetec(TM) reagent grade, 99%
4-(2-Hydroxyethyl)-1-piperazine-3-propanesulfonic acid
FT-0616538
3-[4-(2-hydroxyethyl)piperazin-1-yl]propylsulfonyloxonium;3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid

MDL Number

MFCD00006160

Customs Code

29335995

FAQ

What is 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (CAS: 16052-06-5)?

3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid, with the CAS number 16052-06-5, is a zwitterionic compound commonly used as a buffer in various scientific applications. It has a molecular formula of C8H18N2O5S and is known for its excellent solubility in water and pH stability. This compound is often used in biochemical and pharmaceutical research due to its buffering capacity and mild physiological compatibility.

What are the main uses of 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (CAS: 16052-06-5)?

3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (16052-06-5) is primarily used as a buffer in biochemical and pharmaceutical applications. It is also employed in molecular biology for maintaining pH during experiments such as DNA sequencing and protein analysis. Additionally, it finds use in the formulation of drugs and as a stabilizer in various industrial and research settings.

Is 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (CAS: 16052-06-5) safe?

3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (16052-06-5) is generally considered safe when handled properly. It has low toxicity and is commonly used in laboratory environments. However, standard safety precautions should be followed, such as wearing protective gloves and goggles. It is also important to ensure proper ventilation when working with concentrated solutions to avoid inhalation risks.

How should 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (CAS: 16052-06-5) be stored?

3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid (16052-06-5) should be stored in a cool, dry, and well-ventilated area, away from direct light. It is typically kept in a sealed container to prevent moisture absorption. The optimal storage temperature is between 2°C and 8°C. Proper storage ensures its stability and prevents degradation over time.