trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride | CAS No. 15942-08-2

trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride

Basic Information

CAS Number

15942-08-2

Molecular Formula

C14H19Br2ClN2O

Molecular Weight

426.57 g/mol

AD

Basic Physical Properties

C1CC(CCC1N2CC3=C(C(=CC(=C3)Br)Br)NC2)O.Cl

InChI

InChI=1S/C14H18Br2N2O.ClH/c15-10-5-9-7-18(8-17-14(9)13(16)6-10)11-1-3-12(19)4-2-11;/h5-6,11-12,17,19H,1-4,7-8H2;1H/t11-,12-;

InChIKey

ICLHRFYBPXBCPE-GJTSMBTKSA-N

LogP

4.121900000000004

Topological Polar Surface Area

35.5 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

310

Synonyms & References

English

  • Imp. B (EP) as Hydrochloride: trans-4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)-cyclohexanol Hydrochloride
  • Ambroxol Cyclic Impurity Hydrochloride
  • 4-(6,8-dibromo-2,4-dihydro-1H-quinazolin-3-yl)cyclohexan-1-ol,hydrochloride
  • AMbroxol hydrochloride iMpurity B
  • trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride
  • 4-(6,8-dibromo-2,4-dihydro-1H-quinazolin-3-yl)cyclohexan-1-ol;hydrochloride
  • trans-4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexanol HCl
  • (1r,4r)-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride
  • Cyclohexanol, 4-(6,8-dibromo-1,4-dihydro-3(2H)-quinazolinyl)-, hydrochloride (1:1), trans-
  • trans-4-(6,8-Dibromo
  • metabolites of Bisolvon
  • BS-21599
  • MFCD26967902
  • trans-4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexanol Hydrochloride
  • C14H19Br2ClN2O
  • (1R,4R)-4-(6,8-DIBROMO-2,4-DIHYDRO-1H-QUINAZOLIN-3-YL)CYCLOHEXAN-1-OL HYDROCHLORIDE
  • F12381
  • AMBROXOL CYCLIC IMPURITY HCL
  • CS-0188163
  • EX-7791
  • DTXSID00680609
  • 15942-08-2
  • (1r,4r)-4-(6,8-dibromo-1,2,3,4-tetrahydroquinazolin-3-yl)cyclohexan-1-ol hydrochloride
  • AMbroxol hydrochlorideiMpurity B
  • trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanolhydrochloride
  • AKOS025396549
  • 4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexan-1-ol--hydrogen chloride (1/1)

MDL Number

MFCD26967902

FAQ

What are the physical and chemical properties of trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride (CAS: 15942-08-2)?

The compound is a white crystalline solid with a molecular weight of approximately 462.12 g/mol. It is slightly soluble in water and ethanol. Chemically, it shows moderate reactivity with nucleophiles and exhibits good stability under neutral conditions. It can be identified by its characteristic UV and IR spectra.

How is trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride (CAS: 15942-08-2) typically synthesized?

This compound is usually synthesized through a multi-step process involving bromination of a quinazoline derivative followed by coupling with cyclohexanol. The reaction is catalyzed by palladium-based catalysts and the yield is typically around 70-80%. The method ensures high selectivity and purity.

What industries use trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride (CAS: 15942-08-2)?

This compound is used in the pharmaceutical industry for its potential as a bioactive molecule. It also finds applications in the polymer industry for its specific chemical properties. Additionally, it is explored in sensor technology and semiconductor fabrication due to its unique chemical structure.

What precautions should be taken when handling trans-4-(6,8-dibromo-1,2-dihydroquinazolin-3(4H)-yl)cyclohexanol hydrochloride (CAS: 15942-08-2)?

Proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn when handling this compound. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate solvents and disposed of according to safety data sheet (SDS) guidelines. Always refer to the latest SDS for detailed safety information.

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