Pralmorelin Diacetate Salt

Basic Information

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CAS Number

158861-67-7

Molecular Formula

C45H55N9O6

Molecular Weight

818 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

1265.3°C at 760 mmHg

SMILES

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CC(C(=O)NC(CC1=CC2=CC=CC=C2C=C1)C(=O)NC(C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCCN)C(=O)N)N

InChI

InChI=1S/C45H55N9O6/c1-27(47)41(56)52-38(24-30-19-20-31-14-6-7-15-32(31)22-30)43(58)50-28(2)42(57)53-39(25-33-26-49-35-17-9-8-16-34(33)35)45(60)54-37(23-29-12-4-3-5-13-29)44(59)51-36(40(48)55)18-10-11-21-46/h3-9,12-17,19-20,22,26-28,36-39,49H,10-11,18,21,23-25,46-47H2,1-2H3,(H2,48,55)(H,50,58)(H,51,59)(H,52,56)(H,53,57)(H,54,60)/t27-,28+,36+,37-,38-,39+/m1/s1

InChIKey

HRNLPPBUBKMZMT-RDRUQFPZSA-N

LogP

1.7544000000000046

Topological Polar Surface Area

256.42 Å²

Hydrogen Bond Donor/Acceptor

12 / 15

Complexity

1440

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

GHRP 2
HRNLPPBUBKMZMT-RDRUQFPZSA-N
FT-0656752
GHRP Kaken 100
WAY-GPA-748
GHRP-2
KP 102
CHEMBL106593
(S)-2-((2R,5S,8S,11R,14R)-5-((1H-Indol-3-yl)methyl)-14-amino-2-benzyl-8-methyl-11-(naphthalen-2-ylmethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecanamido)-6-aminohexanamide
D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
L-Lysinamide, D-alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-
D-alanyl-3-(2-naphthyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
D-ALA-3-(2-NAPHTHYL)-D-ALA-ALA-TRP-D-PHE-LYS-NH2
Pralmorelin
d-ala-d-2-nal-ala-trp-d-phe-lys-nh2
Pralmorelin [INN]
Pralmorelin trifluoroacetate salt, >=97% (HPLC)
AKOS037652421
C73002
KP-102D
PRALMORELIN [MI]
UNII-E6S6E1F19M
(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Pralmorelin Diacetate Salt
KP-102
E6S6E1F19M
SCHEMBL424791
KP-102T
158861-67-7
Ala-beta-Nal-Ala-Trp-Phe-Lys-NH2
Q21098924

MDL Number

MFCD00674876

FAQ

What are the physical and chemical properties of Pralmorelin Diacetate Salt (CAS: 158861-67-7)?

Pralmorelin Diacetate Salt is a white crystalline powder. The molecular weight is approximately 534.5 g/mol. It has low solubility in water but is soluble in organic solvents such as ethanol and acetone. It is stable in air and under normal laboratory conditions but reacts with strong bases to form pralmorelin acetate. The compound is not flammable and has a pKa of about 13.0.

How is Pralmorelin Diacetate Salt (CAS: 158861-67-7) typically synthesized?

Pralmorelin Diacetate Salt can be synthesized by acetylation of pralmorelin in the presence of acetic anhydride and an appropriate catalyst like pyridine. The reaction typically proceeds with a yield of around 90%. The product is isolated by crystallization from an organic solvent followed by recrystallization to improve purity.

What industries use Pralmorelin Diacetate Salt (CAS: 158861-67-7)?

Pralmorelin Diacetate Salt is primarily used in the pharmaceutical industry. It is a key intermediate in the synthesis of pralmorelin, a growth hormone-releasing hormone analogue used for research purposes. It may also have applications in the development of new drugs for growth hormone-related disorders.

What precautions should be taken when handling Pralmorelin Diacetate Salt (CAS: 158861-67-7)?

When handling Pralmorelin Diacetate Salt, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and heat sources. In case of a spill, use appropriate containment and clean up with care. Always refer to the Safety Data Sheet (SDS) for detailed safety information.