(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate | CAS No. 15717-45-0
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate
Basic Information
CAS Number
15717-45-0
Molecular Formula
C16H18BrN5O8
Molecular Weight
488.25 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
215-218°C
Boiling Point
673.5°Cat760mmHg
Density
1.94
Flash Point
361.1°C
Refractive Index
1.723
Synonyms & References
English
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate
- Guanosine, 8-bromo-, 2',3',5'-triacetate
- [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-8-bromo-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate
- 2',3',5-Tri-O-acetyl-8-bromoguanosine
- JLZCAXCVNVVXJL-IDTAVKCVSA-N
- E85512
- 8-Bromo-2',3',5'-tri-O-acetylguanosine
- 8-Bromoguanosine 2',3',5'-triacetate
- NS00052009
- (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
- NSC 174056
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyldiacetate
- 15717-45-0
- NSC 79210
- 2',3',5'-Tri-O-acetyl-8-bromoguanosine
- MFCD00057036
- EINECS 239-810-6
- A809817
- SCHEMBL4378875
- AKOS027320601
- 2',3',5'-Tri-O-acetyl-8-bromoadenosine
- Guanosine, 8-bromo-,2',3',5'-triacetate
- 2',3',5'-Tri-O-acetyl-8-broMoguanosine
- 2',3',5-TRI-O-ACETYL-8-BROMOGUANOSINE
- 8-BROMO-2’,3’,5’-TRI-O-ACETYLGUANOSINE
- 2',3',5'.-tri-O-acetyl-8-bromoguanosine
- 2',3',5'-tri-O-acetyl-2-bromoguanosine
- 2',3',5'-Tri-O-acetyl-8-bromo-D-guanosine
- 2'-O,3'-O,5'-O-Triacetyl-8-bromoguanosine
- 8-bromoguanosine 2',3',5'-triacetate
MDL Number
MFCD00057036
FAQ
What are the physical and chemical properties of (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 15717-45-0)?
This compound is a white crystalline solid with a molecular weight of approximately 512.16 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethyl acetate and dichloromethane. The compound is highly reactive and exhibits strong nucleophilic and electrophilic behavior due to its functional groups.
How is (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 15717-45-0) typically synthesized?
This compound is typically synthesized via a multi-step reaction involving the protection of the purine ring with an acetate ester, followed by acetylation of the tetrahydropyran moiety. The reaction is catalyzed by a suitable acid or base, and the overall yield is around 70-80%. The key steps include protecting group installation, acylation, and deprotection.
What industries use (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 15717-45-0)?
This compound is primarily used in the pharmaceutical industry for the development of novel therapeutic agents. Due to its specific chemical structure, it may also find applications in the development of sensors and semiconductors, although its use in these areas is more limited.
What precautions should be taken when handling (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 15717-45-0)?
When handling this compound, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. Operations should be conducted in a well-ventilated fume hood to avoid inhalation of vapors. In case of skin contact, immediately wash with soap and water. For spills, use appropriate spill cleanup kits and follow the Material Safety Data Sheet (MSDS) for disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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