Compound Q&A
How is (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS: 15717-45-0) typically synthesized?
Answer
This compound is typically synthesized via a multi-step reaction involving the protection of the purine ring with an acetate ester, followed by acetylation of the tetrahydropyran moiety. The reaction is catalyzed by a suitable acid or base, and the overall yield is around 70-80%. The key steps include protecting group installation, acylation, and deprotection.
About
CAS No
15717-45-0
English Name
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-bromo-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate
Molecular Formula
C16H18BrN5O8
Molecular Weight
488.25 g/mol
SMILES
CC(=O)OCC1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2Br)OC(=O)C)OC(=O)C
InChIKey
JLZCAXCVNVVXJL-IDTAVKCVSA-N
Last Updated: 2026-01-01 15:34
