1-Bromo-4-ethoxy-2,3-difluorobenzene

Basic Information

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CAS Number

156573-09-0

Molecular Formula

C8H7BrF2O

Molecular Weight

237.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

222.7±35.0 °C at 760 mmHg

Density

1.533

Flash Point

107.2±10.2 °C

Refractive Index

1.497

SMILES

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CCOC1=C(C(=C(C=C1)Br)F)F

InChI

InChI=1S/C8H7BrF2O/c1-2-12-6-4-3-5(9)7(10)8(6)11/h3-4H,2H2,1H3

InChIKey

OJZVBJOHBGYINN-UHFFFAOYSA-N

LogP

3.1260000000000012

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

145

Synonyms & References

English

156573-09-0
AM61339
1-Bromo-4-ethoxy-2,3-difluorobenzene
Benzene, 1-bromo-4-ethoxy-2,3-difluoro-
SCHEMBL1243244
2,3-Difluoro-4-bromophenetole
1-BROMO-4-ETHOXYL-2,3-DIFULOROBENZENE
SY051187
DTXSID00650448
1-Bromo-4-ethoxy-2,3-difluoro-benzene
AKOS015834840
CS-W012863
AC-23886
B3884
1-ethoxy-2,3-difluorobromobenzene
4-Bromo-2,3-difluorophenetole
OJZVBJOHBGYINN-UHFFFAOYSA-N
FT-0730055
BCP27338
MFCD07368018
1-bromo-4-ethoxy-2,3-difluorobenzene-
2,3-Difluoro-4-ethoxybromobenzene
AS-19650
4-Bromo-2,3-Difluorophenetole
4-bromo-2,3-difluoro-ethoxybenzene
B90001
1-Bromo-4-ethoxyl-2,3-difulorobenzene
4-BroMo-2,3-difluorophenyl ethyl ether
5-broMo-1,2-difluoro-3-(MethoxyMethyl)benzene
PubChem10702
KSC496K3P

MDL Number

MFCD07368018

Customs Code

2909309090

FAQ

What are the physical and chemical properties of 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0)?

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is a crystalline solid with a molecular weight of approximately 242.11 g/mol. It is only slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively unreactive toward many common reagents but can undergo substitution reactions under specific conditions. It is stable under normal laboratory conditions but should be stored away from strong oxidizing agents and reducing agents.

How is 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) typically synthesized?

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is typically synthesized through the reaction of 2,3-difluorobenzoic acid with a mixture of bromine and ethyl bromide. The process involves bromination followed by ethoxylation. Optimal conditions include the use of a catalytic amount of a Lewis acid such as aluminum chloride to enhance the reaction rate and yield. The product is isolated by recrystallization from appropriate solvents.

What industries use 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0)?

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is primarily used in the pharmaceutical industry for the synthesis of certain intermediates and final products. It also finds applications in the polymer industry as a monomer or comonomer. Additionally, it has potential uses in the sensor and semiconductor industries, although these applications are less common and more specialized.

What precautions should be taken when handling 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0)?

When handling 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0), ensure the use of appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and incompatible materials. In case of spill, use a fume hood and appropriate spill cleanup materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.