1-Bromo-4-ethoxy-2,3-difluorobenzene(CAS: 156573-09-0)

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is a crystalline solid with a molecular weight of approximately 242.11 g/mol. It is only slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively unreactive toward many common reagents but can undergo substitution reactions under specific conditions. It is stable under normal laboratory conditions but should be stored away from strong oxidizing agents and reducing agents.

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is typically synthesized through the reaction of 2,3-difluorobenzoic acid with a mixture of bromine and ethyl bromide. The process involves bromination followed by ethoxylation. Optimal conditions include the use of a catalytic amount of a Lewis acid such as aluminum chloride to enhance the reaction rate and yield. The product is isolated by recrystallization from appropriate solvents.

1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0) is primarily used in the pharmaceutical industry for the synthesis of certain intermediates and final products. It also finds applications in the polymer industry as a monomer or comonomer. Additionally, it has potential uses in the sensor and semiconductor industries, although these applications are less common and more specialized.

When handling 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS: 156573-09-0), ensure the use of appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and incompatible materials. In case of spill, use a fume hood and appropriate spill cleanup materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.