2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate

Basic Information

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CAS Number

154048-89-2

Molecular Formula

C10H13IN2O2

Molecular Weight

320.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

72-76 ºC

Boiling Point

313.221℃ at 760 mmHg

SMILES

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CC(C)(C)OC(=O)NC1=C(C=CN=C1)I

InChI

InChI=1S/C10H13IN2O2/c1-10(2,3)15-9(14)13-8-6-12-5-4-7(8)11/h4-6H,1-3H3,(H,13,14)

InChIKey

FUKNUVWILSPUSJ-UHFFFAOYSA-N

LogP

3.033200000000001

Topological Polar Surface Area

51.22 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

228

Synonyms & References

English

TERT-BUTYL N-(4-IODOPYRIDIN-3-YL)CARBAMATE
(4-lodo-pyridin-3-yl)carbamic acid tert-butyl ester
(4-iodopyridin-3-yl)carbamic acid tert-butyl ester
FUKNUVWILSPUSJ-UHFFFAOYSA-N
tert-Butyl (4-iodopyridin-3-yl)carbamate
(4-IODO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
DS-12301
F14805
CS-M1250
(4-Iodo-3-pyridinyl)-carbamic acid tert-butyl ester
tert-butyl N-(4-iodo-3-pyridyl)carbamate
FT-0650881
154048-89-2
TERT-BUTYL 4-IODOPYRIDIN-3-YLCARBAMATE
J-009065
MFCD04973410
N-Boc-3-Amino-4-iodopyridine
AKOS015911274
AC-14684
3-(Boc-amino)-4-iodopyridine
SCHEMBL1635061
SY041390
EN300-7404362
N-tert-Butoxycarbonyl-3-amino-4-iodo-pyridine
N-Boc--3-AMino-4-iodopyridine
(4-IODO-3-PYRIDINYL)-CARBAMIC ACID, 1,1-DIMETHYLETHYL ESTER
Carbamic acid,N-(4-iodo-3-pyridinyl)-, 1,1-dimethylethyl ester
N-TERT-BUTOXYCARBONYL-3-AMINO-4-IODO-PYRIDINE
tert-butyl 4-iodopyridin-3-ylcarbaMate
FCH1618079
tert-butyl N-(4-iodo-3-p

MDL Number

MFCD04973410

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate (CAS: 154048-89-2)?

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate is a crystalline compound with a molecular weight of approximately 285.03 g/mol. It has low solubility in water but good solubility in organic solvents like methanol and ethanol. Chemically, it is stable but can react with strong bases and reducing agents. It has a melting point of around 118-120°C and is non-volatile.

How is 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate (CAS: 154048-89-2) typically synthesized?

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate can be synthesized via a multi-step process involving the reaction of 2-methyl-2-propanol with 4-iodo-3-pyridinecarbonyl chloride in the presence of a base like triethylamine. The yield is typically around 70-75%, and the reaction is carried out in an anhydrous organic solvent at room temperature.

What industries use 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate (CAS: 154048-89-2)?

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate is used primarily in the synthesis of various pharmaceuticals and as an intermediate in the development of new chemical entities. It also finds applications in the production of certain polymers and as a reagent in analytical chemistry and material science.

What precautions should be taken when handling 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate (CAS: 154048-89-2)?

When handling 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up with care, using appropriate absorbents, and the area should be thoroughly washed down. Always consult the Safety Data Sheet (SDS) for detailed information and guidelines.