2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate(CAS: 154048-89-2)

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate is a crystalline compound with a molecular weight of approximately 285.03 g/mol. It has low solubility in water but good solubility in organic solvents like methanol and ethanol. Chemically, it is stable but can react with strong bases and reducing agents. It has a melting point of around 118-120°C and is non-volatile.

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate can be synthesized via a multi-step process involving the reaction of 2-methyl-2-propanol with 4-iodo-3-pyridinecarbonyl chloride in the presence of a base like triethylamine. The yield is typically around 70-75%, and the reaction is carried out in an anhydrous organic solvent at room temperature.

2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate is used primarily in the synthesis of various pharmaceuticals and as an intermediate in the development of new chemical entities. It also finds applications in the production of certain polymers and as a reagent in analytical chemistry and material science.

When handling 2-Methyl-2-propanyl (4-iodo-3-pyridinyl)carbamate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up with care, using appropriate absorbents, and the area should be thoroughly washed down. Always consult the Safety Data Sheet (SDS) for detailed information and guidelines.