1-(5-Phenyl-1,2-oxazol-3-yl)methanamine

Basic Information

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CAS Number

154016-47-4

Molecular Formula

C10H10N2O

Molecular Weight

174.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1=CC=C(C=C1)C2=CC(=NO2)CN

InChI

InChI=1S/C10H10N2O/c11-7-9-6-10(13-12-9)8-4-2-1-3-5-8/h1-6H,7,11H2

InChIKey

GWDSZTSDAULPDO-UHFFFAOYSA-N

LogP

1.8003

Topological Polar Surface Area

52.05 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

157

Synonyms & References

English

154016-47-4
GWDSZTSDAULPDO-UHFFFAOYSA-N
CCG-309975
(5-phenyl-1,2-oxazol-3-yl)methanamine
EN300-64230
(5-Phenyl-isoxazol-3-yl)methylamine
I11105
C-(5-Phenylisoxazol-3-yl)methylamine
(5-Phenylisoxazol-3-yl)methanamine
MFCD06738927
SCHEMBL1457325
AS-49509
DTXSID60409439
Z992722204
C-(5-Phenyl-isoxazol-3-yl)-methylamine
(5-phenylisoxazol-3-yl)methylamine
FT-0697740
F2158-1059
J-009058
AKOS003673984
(5-PHENYL-3-ISOXAZOLYL)METHANAMINE
AB28197
CS-0005458
(5-PHENYLISOXAZOL-3-YL)METHYLAMINE
3-Isoxazolemethanamine,5-phenyl-
C-(5-Phenyl-isoxazol-3-yl)-methylamine hydrochloride
AKOS PAO-1454
C-(5-PHENYL-ISOXAZOL-3-YL)-METHYLAMINE
1-(5-Phenyl-1,2-oxazol-3-yl)methanamine
004801
CBI-BB ZERO

MDL Number

MFCD06738927

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine (CAS: 154016-47-4)?

1-(5-Phenyl-1,2-oxazol-3-yl)methanamine is a crystalline solid at room temperature. Its molecular weight is approximately 210.23 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly towards nucleophiles and bases. It is stable under normal storage conditions but should be protected from strong acids and oxidizing agents.

How is 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine (CAS: 154016-47-4) typically synthesized?

1-(5-Phenyl-1,2-oxazol-3-yl)methanamine can be synthesized through the reaction of 5-phenyl-3-(methoxymethyl)oxazole with ammonia or an amine under basic conditions. The key steps involve the formation of the oxazolone ring followed by deprotection to form the amine. This process usually involves mild base catalysis and yields up to 85% purity.

What industries use 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine (CAS: 154016-47-4)?

1-(5-Phenyl-1,2-oxazol-3-yl)methanamine is primarily used in the pharmaceutical industry for the development of novel drugs. It is also utilized in polymer chemistry for modifying materials and in sensor technology for detecting specific chemical species. Its applications in semiconductors are limited but it can be used as a dopant in certain semiconductor devices.

What precautions should be taken when handling 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine (CAS: 154016-47-4)?

When handling 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines and disposal procedures.