Compound Q&A

How is 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine (CAS: 154016-47-4) typically synthesized?

Answer

1-(5-Phenyl-1,2-oxazol-3-yl)methanamine
1-(5-Phenyl-1,2-oxazol-3-yl)methanamine can be synthesized through the reaction of 5-phenyl-3-(methoxymethyl)oxazole with ammonia or an amine under basic conditions. The key steps involve the formation of the oxazolone ring followed by deprotection to form the amine. This process usually involves mild base catalysis and yields up to 85% purity.

About

English Name 1-(5-Phenyl-1,2-oxazol-3-yl)methanamine
Molecular Formula C10H10N2O
Molecular Weight 174.203 g/mol
SMILES C1=CC=C(C=C1)C2=CC(=NO2)CN
InChIKey GWDSZTSDAULPDO-UHFFFAOYSA-N
Last Updated: 2026-01-13 10:36

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