4-Fluoronicotinic acid

Basic Information

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CAS Number

152126-33-5

Molecular Formula

C6H4FNO2

Molecular Weight

141.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

284.9±20.0 ºC (760 Torr),

Flash Point

126.1±21.8 ºC,

SMILES

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C1=CN=CC(=C1F)C(=O)O

InChI

InChI=1S/C6H4FNO2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H,9,10)

InChIKey

UBIVUIKWHBNGFG-UHFFFAOYSA-N

LogP

0.9189

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

140

Synonyms & References

English

4-fluoranylpyridine-3-carboxylic acid
SCHEMBL229353
4-fluoro-3-pyridinecarboxylic acid
CS-0040491
4-fluoropyridine-3-carboxylic Acid
AB18036
CS-13273
3-Pyridinecarboxylicacid, 4-fluoro-
MFCD04114256
FT-0688510
4-fluoronicotinic acid
CHEMBL247324
AKOS006293670
4-Fluoropyridine-3-carboxylic
4-Fluoropyridine-3-carboxylicacid
152126-33-5
BCP21970
W18401
A809263
DTXSID00376590
AMY42380
4-Fluoropyridine-3-carboxylic acid
4-FLUORONICOTINIC ACID
3-Pyridinecarboxylicacid,4-fluoro
4-Fluoropyridin-3-carboxylic acid
3-Pyridinecarboxylicacid,4-fluoro-(9CI)
4-FLUORO-NICOTINIC ACID
PubChem10434
7628AA
WT2044
FCH848881

MDL Number

MFCD04114256

FAQ

What are the physical and chemical properties of 4-Fluoronicotinic acid (CAS: 152126-33-5)?

4-Fluoronicotinic acid (CAS: 152126-33-5) is a white or off-white crystalline solid with a molecular weight of approximately 137.02 g/mol. It is slightly soluble in water and ethanol. The compound is mildly acidic and can react with bases to form salts. It is stable under normal conditions but may decompose at high temperatures or in strongly basic solutions.

How is 4-Fluoronicotinic acid (CAS: 152126-33-5) typically synthesized?

4-Fluoronicotinic acid is typically synthesized by fluorinating nicotinic acid. This process can be achieved using phosphorus pentachloride as a fluorinating agent. The reaction is usually carried out in a suitable solvent such as dichloromethane. The product is then purified through recrystallization to obtain the crystalline form.

What industries use 4-Fluoronicotinic acid (CAS: 152126-33-5)?

4-Fluoronicotinic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the development of chemical sensors and in the production of various organic compounds. Additionally, it can be used in the preparation of certain electronic materials.

What precautions should be taken when handling 4-Fluoronicotinic acid (CAS: 152126-33-5)?

When handling 4-Fluoronicotinic acid (CAS: 152126-33-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using an appropriate absorbent material. Always consult the safety data sheet (SDS) for detailed safety information and emergency procedures.