4-Fluoronicotinic acid(CAS: 152126-33-5)

4-Fluoronicotinic acid (CAS: 152126-33-5) is a white or off-white crystalline solid with a molecular weight of approximately 137.02 g/mol. It is slightly soluble in water and ethanol. The compound is mildly acidic and can react with bases to form salts. It is stable under normal conditions but may decompose at high temperatures or in strongly basic solutions.

4-Fluoronicotinic acid is typically synthesized by fluorinating nicotinic acid. This process can be achieved using phosphorus pentachloride as a fluorinating agent. The reaction is usually carried out in a suitable solvent such as dichloromethane. The product is then purified through recrystallization to obtain the crystalline form.

4-Fluoronicotinic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the development of chemical sensors and in the production of various organic compounds. Additionally, it can be used in the preparation of certain electronic materials.

When handling 4-Fluoronicotinic acid (CAS: 152126-33-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using an appropriate absorbent material. Always consult the safety data sheet (SDS) for detailed safety information and emergency procedures.