Compound Q&A

How is 4-Fluoronicotinic acid (CAS: 152126-33-5) typically synthesized?

Answer

4-Fluoronicotinic acid
4-Fluoronicotinic acid is typically synthesized by fluorinating nicotinic acid. This process can be achieved using phosphorus pentachloride as a fluorinating agent. The reaction is usually carried out in a suitable solvent such as dichloromethane. The product is then purified through recrystallization to obtain the crystalline form.

About

English Name 4-Fluoronicotinic acid
Molecular Formula C6H4FNO2
Molecular Weight 141.10099999999997 g/mol
SMILES C1=CN=CC(=C1F)C(=O)O
InChIKey UBIVUIKWHBNGFG-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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