(4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole) | CAS No. 150639-34-2

(4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole)

Basic Information

CAS Number

150639-34-2

Molecular Formula

C19H18N2O2

Molecular Weight

306.36 g/mol

AD

Basic Physical Properties

C1C(N=C(O1)CC2=NC(CO2)C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChI=1S/C19H18N2O2/c1-3-7-14(8-4-1)16-12-22-18(20-16)11-19-21-17(13-23-19)15-9-5-2-6-10-15/h1-10,16-17H,11-13H2/t16-,17-/m0/s1

InChIKey

IUFHJPXOLHSJTC-IRXDYDNUSA-N

LogP

3.7165000000000026

Topological Polar Surface Area

43.18000000000001 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

420

Synonyms & References

English

  • MFCD00978440
  • (R,R)-2,2'-METHYLENEBIS(4-PHENYL-2-OXAZOLINE)
  • (4R)-4-phenyl-2-[[(4R)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole
  • 150639-34-2
  • CS-0093230
  • Bis(cis-4-phenyl-4,5-dihydrooxazol-2-yl)methane
  • SCHEMBL248238
  • 4-phenyl-2-[(4-phenyl-4,5-dihydro-1,3-oxazol-2-yl)methyl]-4,5-dihydro-1,3-oxazole
  • (R,R)-2,2-Methylenebis(4-phenyl-2-oxazoline)
  • J-006123
  • Oxazole, 2,2'-methylenebis[4,5-dihydro-4-phenyl-, (4R,4'R)-
  • (4R,4'R)-2,2'-methylenebis[4,5-dihydro-4-phenyloxazole]
  • (R,R)-2,2/'-METHYLENEBIS(4-PHENYL-2-OXAZOLINE)
  • BS-49402
  • E76044
  • 2,2'-Methylenebis[(4S)-4-phenyl-2-oxazoline]
  • 188255-27-8
  • 1,2-d]oxazole]
  • 2,2'-methylene-b
  • 2,2'-methylenebis[(4R)-4-phenyl]-4,5-dihydro-2-oxazole
  • 2,2'-methylenebis[(4R)-4-phenyl-4,5-dihydro-2-oxazole]
  • 2,2'-methylenebis[(4S)-4-phenyl-2-oxazoline]
  • 467073_ALDRICH
  • Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)methane
  • bis((3aS,8aR)-8,8a-dihydro-indeno[1,2-d]oxazol-2-yl)methane
  • bis((R)-4-phenyl-4,5-dihydrooxazol-2-yl)methane
  • CTK8B1014
  • (4R,4'R)-2,2'-methylenebis[4,5-dihydro-4-phenyl-Oxazole

MDL Number

MFCD01075228

FAQ

What are the physical and chemical properties of (4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole) (CAS: 150639-34-2)?

This compound is a white crystalline solid with a molecular weight of approximately 316.30 g/mol. It has a moderate solubility in common organic solvents such as ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is also known for its low volatility and good stability under normal conditions.

How is (4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole) (CAS: 150639-34-2) typically synthesized?

This compound is commonly synthesized via a condensation reaction of 4-phenyl-4,5-dihydro-1,3-oxazole with benzaldehyde, followed by a Wittig reaction using triphenylphosphonium methoxide. The process involves the use of a solvent such as toluene and typically yields a product with good selectivity and moderate to high yield depending on the reaction conditions.

What industries use (4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole) (CAS: 150639-34-2)?

This compound is used in the pharmaceutical industry for its potential as a drug precursor, in sensor technology due to its sensitivity to certain analytes, and in the semiconductor industry for its use in organic electronic devices. It also finds applications in the polymer industry for its excellent thermal and chemical stability.

What precautions should be taken when handling (4R,4'R)-2,2'-Methylenebis(4-phenyl-4,5-dihydro-1,3-oxazole) (CAS: 150639-34-2)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling this compound. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be rinsed with water. Always refer to the Safety Data Sheet (SDS) for specific handling and safety information.

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