CFDA-SE | CAS No. 150347-59-4

CFDA-SE

Basic Information

View in Editor

CAS Number

150347-59-4

Molecular Formula

C29H19NO11

Molecular Weight

557.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

152-154 °C

SMILES

View in Editor

CC(OC1=CC=C(C2(C(C=CC(C(ON3C(CCC3=O)=O)=O)=C4)=C4C(O2)=O)C(C=CC(OC(C)=O)=C5)=C5O6)C6=C1)=O.CC(OC7=CC=C(C8(C(C=C(C(ON9C(CCC9=O)=O)=O)C=C%10)=C%10C(O8)=O)C(C=CC(OC(C)=O)=C%11)=C%11O%12)C%12=C7)=O

InChIKey

QSWYNOQSGMUDQZ-UHFFFAOYSA-N

LogP

3.26390

pKa

6.45(at 25℃)

Complexity

2190

Safety Information

View Safety Information

Sensitiveness

对光及湿度敏感

Synonyms & References

English

CARBOXYFLUORESCEIN DIACETATE, NHS ESTER
CFSE
5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXY-SUCCINIMIDE ESTER
5(6)-CARBOXYFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER
5-CARBOXYFLUORESCEIN-NHS DIACETATE
5-CARBOXY-DI-O-ACETYLFLUORESCEIN N-SUCCINIMIDYL ESTER
5-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER
5-CARBOXY-FLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylicacid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
5(6)-Carboxyfluorescein diacetate, succinimidyl ester（CFDA）
≥90 (HPCE)
5(6)-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester
5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER
5-CFDA, SE [5-Carboxyfluorescein diacetate succinimidyl ester]
Cellstain CFSE
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylicacid, 3',6'-bis(acetyloxy)-3-oxo-, 2,5...
5(6)-Carboxyfluorescein diacetate N-succinimidyl ester
5(6)-Carboxyfluorescein diacetate succinimidyl ester
5(6)-CFDA N-succinmidyl ester
CFDA-SE
CFDA SE
NHS ester
5(6)-FAM DA SE
-Cellstain-Cfse
5-FAM-NHS DIACETATE
Carboxyfluorescein diacetate, succinimidyl ester
5(6)-CFDA (SE [5(6)-Carboxyfluorescein diacetate

MDL Number

MFCD00037466

Customs Code

32129000

FAQ

What are the physical and chemical properties of CFDA-SE (CAS: 150347-59-4)?

CFDA-SE (CAS: 150347-59-4) is a crystalline compound with a molecular weight of approximately 322.3 g/mol. It has a solubility of 2.5 mg/mL in water and is slightly soluble in common organic solvents like ethanol and acetone. CFDA-SE exhibits low reactivity under normal conditions but may undergo hydrolysis in the presence of strong acids or bases. It is stable at room temperature but should be stored in a cool, dark place to maintain its integrity.

How is CFDA-SE (CAS: 150347-59-4) typically synthesized?

CFDA-SE (CAS: 150347-59-4) is typically synthesized through a multi-step procedure involving the coupling of 4-chlorobenzenesulfonic acid with N,N-dimethylformamide (DMF) in the presence of a catalyst such as 4-(dimethylamino)pyridine (DMAP). The reaction is carried out under mild conditions with good selectivity and yield, resulting in a crystalline product that can be purified by recrystallization.

What industries use CFDA-SE (CAS: 150347-59-4)?

CFDA-SE (CAS: 150347-59-4) is primarily used in the pharmaceutical industry for drug development and synthesis. It also finds applications in the polymer industry for enhancing certain properties of polymers, in sensor technology for specific chemical detection, and in semiconductor manufacturing for etching and cleaning processes.

What precautions should be taken when handling CFDA-SE (CAS: 150347-59-4)?

When handling CFDA-SE (CAS: 150347-59-4), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The material should be stored in a fume hood to minimize exposure to air and to prevent inhalation. In the event of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the safety data sheet (SDS) for detailed handling and emergency procedures.