1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]

Basic Information

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CAS Number

1498-88-0

Molecular Formula

C19H18N2O3

Molecular Weight

322.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

179-180 °C

Boiling Point

460.98°C (rough estimate)

Refractive Index

1.6140 (estimate)

SMILES

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[O-][N+](=O)c1ccc2c(c1)C=CC1(O2)N(C)c2c(C1(C)C)cccc2

InChI

InChI=1S/C19H18N2O3/c1-18(2)15-6-4-5-7-16(15)20(3)19(18)11-10-13-12-14(21(22)23)8-9-17(13)24-19/h4-12H,1-3H3

InChIKey

PSXPTGAEJZYNFI-UHFFFAOYSA-N

LogP

4.71250

Complexity

555

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Spiro[2H-1-benzopyran-2,2'-[2H]indole],1',3'-dihydro-1',3',3'-trimethyl-6-nitro-
1,3,3-Trimethylindolino-6'-nitrobenzopyrylospiran [Photochromic Compound]
1,3,3-TRIMETHYLINDOLINO-6'-NITROBENZOPYRYLOSPIRAN
1',3',3'-Trimethyl-6-nitrospiro[1(2H)-benzopyran-2,2'-indoline]
1',3',3'-trimethyl-6-nitrospiro[chromene-2,2'-indole]
1',3',3'-Trimethyl-6-nitrospiro[chromene-2,2'-indoline]
6-Nitro-1',3',3'-trimethylspiro[2H-benzopyran-2,2'-indoline]
6'-Nitro-1,3,3-trimethylspiro[2'H-1'-benzopyran-2',2-indoline]
6'-Nitro-1,3,3-trimethylspiro[indoline-2,2'-2'H-chromene]
NSC 206176
SP 1
SP 1 (dye)
AKOS 90425
1' 3'-DIHYDRO-1' 3' 3'-TRIMETHYL-6-NITR&
6'-Nitro-1,3,3-trimethylindolinobenzopyrylspiran
1,3,3-Trimethylindolino-6-nitrobenzopyrylospirane
1,3,3-trimethyl-6'-nitroindole-2-spiro-2'-benzopyran
1',3'-dihydro-1',3',3'-trimethyl-6-nitro-spiro(2H
Spiro[2H-1-benzopyran-2,2'-[2H]indole], 1',3'-dihydro-1',3',3'-trimethyl-6-nitro-
Spiro[2H-1-benzopyran-2,2'-indoline], 1',3',3'-trimethyl-6-nitro-
1,3,3-Trimethyl-6'-nitroindoline-2-spiro-2'-benzopyran
Spiro(2H-1-benzopyran-2,2'-indoline), 6-nitro-1',3',3'-trimethyl-
1',3',3'-Trimethyl-6-nitro

MDL Number

MFCD00059175

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 1498-88-0)?

1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] is a crystalline solid with a molecular weight of approximately 314.12 g/mol. It is slightly soluble in organic solvents such as ethanol and acetone. This compound is known for its reactive nature, particularly towards nucleophiles and reducing agents. It exhibits good stability under normal storage conditions but requires care when handling due to its potential reactivity.

How is 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 1498-88-0) typically synthesized?

1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] is typically synthesized via a multi-step process involving the protection of chromene, followed by nitration and subsequent deprotection. Commonly used catalysts include sulfonic acids, and the reaction is carried out under controlled conditions to achieve high selectivity and yield. Detailed protocols can be found in literature sources.

What industries use 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 1498-88-0)?

1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] has applications in the pharmaceutical industry, where it is used as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the development of functional polymers, and in the electronics sector for the production of organic light-emitting diodes (OLEDs) and other semiconductor devices.

What precautions should be taken when handling 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 1498-88-0)?

When handling 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole], it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.