Compound Q&A

How is 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 1498-88-0) typically synthesized?

Answer

1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]
1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] is typically synthesized via a multi-step process involving the protection of chromene, followed by nitration and subsequent deprotection. Commonly used catalysts include sulfonic acids, and the reaction is carried out under controlled conditions to achieve high selectivity and yield. Detailed protocols can be found in literature sources.

About

CAS No 1498-88-0
English Name 1',3',3'-Trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]
Molecular Formula C19H18N2O3
Molecular Weight 322.36 g/mol
SMILES [O-][N+](=O)c1ccc2c(c1)C=CC1(O2)N(C)c2c(C1(C)C)cccc2
InChIKey PSXPTGAEJZYNFI-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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