2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate

Basic Information

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CAS Number

147611-03-8

Molecular Formula

C13H24N2O2

Molecular Weight

240.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

362 ºC

Flash Point

173 ºC

SMILES

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CC(C)(C)OC(=O)NC1CC2(C1)CCNCC2

InChI

InChI=1S/C13H24N2O2/c1-12(2,3)17-11(16)15-10-8-13(9-10)4-6-14-7-5-13/h10,14H,4-9H2,1-3H3,(H,15,16)

InChIKey

UXSKWUIJYPVHKK-UHFFFAOYSA-N

LogP

2.0433

Topological Polar Surface Area

50.36 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

282

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

tert-Butyl 7-azaspiro[3.5]nonan-2-ylcarbamate
2-(Boc-amino)-7-azaspiro[3.5]nonane
Carbamic acid, 7-azaspiro[3.5]non-2-yl-, 1,1-dimethylethyl ester (9CI)
tert-Butyl 7-azaspiro[3.5]non-2-ylcarbamate
7-Azaspiro[3.5]non-2-yl-carbamic acid tert-butyl ester
7-Azaspiro[3.5]nonane carbamic acid deriv
2-(tert-Butoxycarbonylamino)-7-azaspiro[3.5]nonane
tert-butyl N-{7-azaspiro[3.5]nonan-2-yl}carbamate
N-7-Azaspiro[3.5]non-2-yl-carbamic acid tert-butyl ester
CarbaMic acid, N-7-azaspiro[3.5]non-2-yl-, 1,1-diMethylethyl ester
TERT-BUTYL N-(7-AZASPIRO[3.5]NONAN-2-YL)CARBAMATE
UXSKWUIJYPVHKK-UHFFFAOYSA-N
BCP21594
WT1150
PB26785
FCH1621060
2-N-Boc-amino-7-azaspiro[3.5]nonane
AM803234
OR317096
EN00

MDL Number

MFCD12198553

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate (CAS: 147611-03-8)?

2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate is a colorless solid with a pungent odor. It has a molecular weight of approximately 320.4 g/mol and is soluble in organic solvents like methanol and ethyl acetate. The compound is relatively stable under normal conditions but can react with strong acids and bases. It is not flammable and has a melting point of 65-67°C.

How is 2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate (CAS: 147611-03-8) typically synthesized?

2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate is commonly synthesized via a multistep process involving alkylation and amidation reactions. The key steps include the preparation of the azaspiro derivative from a primary amine and a ketone, followed by alkylation with 2-methyl-2-propanol. The reaction is typically carried out under basic conditions, and yields can be improved by careful selection of catalysts and solvents.

What industries use 2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate (CAS: 147611-03-8)?

2-Methyl-2-propanyl 7-azaspiro[3.5]non-2-ylcarbamate finds applications in the pharmaceutical and fine chemical industries. It serves as a precursors for the synthesis of various bioactive compounds and has potential uses in medicinal chemistry and drug discovery. Additionally, it may be used in the development of novel materials for electronic applications due to its electronic properties.

What precautions should be taken when handling 2-Methyl-2-proanyl 7-azaspiro[3.5]non-2-ylcarbamate (CAS: 147611-03-8)?

Proper handling of 2-Methyl-2-proanyl 7-azaspiro[3.5]non-2-ylcarbamate requires the use of appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place, away from heat sources and incompatible materials. In case of a spill, it should be carefully cleaned up using absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for specific handling instructions and emergency procedures.